Publication:
Factors associated with seropositive antibodies to Brucella melitensis in the Nakhon Nayok, Thailand

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Issued Date

2012

Resource Type

Article

File Type

application/pdf

ISSN

1252208

Other identifier(s)

2-s2.0-84876894982

Rights Holder(s)

Scopus

Bibliographic Citation

Journal of the Medical Association of Thailand. Vol 95, No.SUPPL.12 (2012), p.S40-S46

Suggested Citation

Ekpanyaskul C., Santiwattanakul S., Tantisiriwat W., Buppanharun W. Factors associated with seropositive antibodies to Brucella melitensis in the Nakhon Nayok, Thailand. Journal of the Medical Association of Thailand. Vol 95, No.SUPPL.12 (2012), p.S40-S46. Retrieved from: https://hdl.handle.net/20.500.14740/6862

Title

Factors associated with seropositive antibodies to Brucella melitensis in the Nakhon Nayok, Thailand

Author(s)

Ekpanyaskul C.
 Santiwattanakul S.
 Tantisiriwat W.
 Buppanharun W.

Abstract

Backgroud: Human brucellosis is a re-emerging disease in Thailand. In 2006, Her Royal Highness Princess Maha Chakri Sirindhorn Medical Center, Nakorn Nayok province had diagnosed three cases of brucellosis which have never been reported in this area. Objective: To conduct an epidemiologic study with the aim of evaluating the sero-prevalence and factors associated with seropositive antibodies to Brucella melitensis among residents who live in the same sub-district of the first index case. Material and Method: In 2007, a study was conducted in Chumpon sub-district, Ongkharak district, Nakhon Nayok province, Thailand where the outbreak took place in the previous year. The 86 subjects were selected from three villages in the present study area. Blood specimens were collected and tested for antibodies for Brucella melitensis using a serum agglutination test. A structural interview questionnaire was used to detect any possible risk factors. A binary logistic regression was utilized for analyzing the statistical data. Results: Of all participants in the present study, 45.35% (95% CI; 34.61-56.08%) had seropositive antibodies to Brucella melitensis. Multivariate analysis indicated that factors associated with seropositive titers were highly related to contact with labored or aborted goats, adjusted odds ratio = 27.16 (95% CI = 1.02-721.53) and the consumption of raw goat products, adjusted odds ratio = 6.27 (95% CI = 1.25-31.36). Conclusion: High seropositive prevalence of Brucella melitenis after the 2006 outbreak was found in the present study. The associated factors of infection are direct contact with infected animals and this is similar with the other outbreak areas in Thailand and the endemic countries. Therefore, local authorities should not only provide the communities with health education, but also conduct continued surveillance in order to help control and prevent the epidemic.

Subject(s)

Adult
 Agglutination test
 Article
 Brucella melitensis
 Brucellosis
 Community program
 Cross-sectional study
 Disease surveillance
 Female
 Health education
 Human
 Infection control
 Infection prevention
 Infection risk
 Major clinical study
 Male
 Questionnaire
 Risk factor
 Serodiagnosis
 Seroprevalence
 Thailand
 Adolescent
 Adult
 Aged
 Animals
 Antibodies, Bacterial
 Brucellosis
 Cattle
 Cattle Diseases
 Cross-Sectional Studies
 Disease Outbreaks
 Female
 Goat Diseases
 Goats
 Humans
 Logistic Models
 Male
 Middle Aged
 Questionnaires
 Risk Factors
 Seroepidemiologic Studies
 Serologic Tests
 Thailand

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URI

https://hdl.handle.net/20.500.14740/6862

Collections

Scopus: Year 1983-2021

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