Publication:
A new α-pyrone derivative from Annulohypoxylon stygium SWUF09-030

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Issued Date

2020

Resource Type

Article

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application/pdf

ISSN

10286020

DOI

10.1080/10286020.2020.1856095

Other identifier(s)

2-s2.0-85097763387

Rights Holder(s)

Scopus

Bibliographic Citation

Journal of Asian Natural Products Research. (2020)

Suggested Citation

Pimjuk P., Mongkolthanaruk W., Suwannasai N., Senawong T., Tontapha S., Amornkitbumrung V., Mccloskey S. A new α-pyrone derivative from Annulohypoxylon stygium SWUF09-030. Journal of Asian Natural Products Research. (2020). doi:10.1080/10286020.2020.1856095 Retrieved from: https://hdl.handle.net/20.500.14740/4871

Title

A new α-pyrone derivative from Annulohypoxylon stygium SWUF09-030

Author(s)

Pimjuk P.
 Mongkolthanaruk W.
 Suwannasai N.
 Senawong T.
 Tontapha S.
 Amornkitbumrung V.
 Mccloskey S.

Abstract

A new α-pyrone derivative, namely annulopyronoate (1), together with the known isobenzofuranone, diphenyl ether, sesquiterpene, phenolic and diketopiperazine derivatives (2–12) were isolated from a filamentous fungus Annulohypoxylon stygium SWUF09-030. The structures were determined by analysis of spectroscopic and MS data. The absolute configuration of 1 was determined by comparison of experimental and calculated Electronic Circular Dichroism (ECD) spectra. Compounds 3–5 and 7 exhibited both anti-proliferative effects against HeLa, HT29, HCT116, MCF-7 and Vero cell lines and inhibition of nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophage cells. © 2020 Informa UK Limited, trading as Taylor & Francis Group.

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URI

https://hdl.handle.net/20.500.14740/4871

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Scopus: Year 1983-2021

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