Publication:
Low-cost and disposable sensors for the simultaneous determination of coenzyme Q10 and α-lipoic acid using manganese (IV) oxide-modified screen-printed graphene electrodes

2
0

Issued Date

2018

Resource Type

Article

File Type

application/pdf

ISSN

32670

DOI

10.1016/j.aca.2017.12.026

Other identifier(s)

2-s2.0-85039942501

Rights Holder(s)

Scopus

Bibliographic Citation

Analytica Chimica Acta. Vol 1004, (2018), p.22-31

Suggested Citation

Charoenkitamorn K., Chaiyo S., Chailapakul O., Siangproh W. Low-cost and disposable sensors for the simultaneous determination of coenzyme Q10 and α-lipoic acid using manganese (IV) oxide-modified screen-printed graphene electrodes. Analytica Chimica Acta. Vol 1004, (2018), p.22-31. doi:10.1016/j.aca.2017.12.026 Retrieved from: https://hdl.handle.net/20.500.14740/5931

Title

Low-cost and disposable sensors for the simultaneous determination of coenzyme Q10 and α-lipoic acid using manganese (IV) oxide-modified screen-printed graphene electrodes

Author(s)

Charoenkitamorn K.
 Chaiyo S.
 Chailapakul O.
 Siangproh W.

Abstract

In this work, for the first time, manganese (IV) oxide-modified screen-printed graphene electrodes (MnO2/SPGEs) were developed for the simultaneous electrochemical detection of coenzyme Q10 (CoQ10) and α-lipoic acid (ALA). This sensor exhibits attractive benefits such as simplicity, low production costs, and disposability. Cyclic voltammetry (CV) was used to characterize the electrochemical behavior of the analyte and investigate the capacitance and electroactive surface area of the unmodified and modified electrode surfaces. The electrochemical behavior of CoQ10 and ALA on MnO2/SPGEs was also discussed. Additionally, square wave anodic stripping voltammetry (SWASV) was used for the quantitative determination of CoQ10 and ALA. Under optimal conditions, the obtained signals are linear in the concentration range from 2.0 to 75.0 μg mL−1 for CoQ10 and 0.3–25.0 μg mL−1 for ALA. The low limits of detection (LODs) were found to be 0.56 μg mL−1 and 0.088 μg mL−1 for CoQ10 and ALA, respectively. Moreover, we demonstrated the utility and applicability of the MnO2/SPGE sensor through simultaneous measurements of CoQ10 and ALA in dietary supplements. The sensor provides high accuracy measurements, exhibiting its high potential for practical applications. © 2017 Elsevier B.V.

Subject(s)

Chemical detection
 Coenzymes
 Cyclic voltammetry
 Dietary supplements
 Graphene
 Graphite electrodes
 Manganese oxide
 Coenzyme Q10
 Electroactive surface areas
 Lipoic acids
 Modified electrode surfaces
 Quantitative determinations
 Screen-printed graphene electrodes
 Simultaneous determinations
 Square wave anodic stripping voltammetry
 Electrochemical electrodes
 Graphene
 Manganese oxide
 Thioctic acid
 Ubidecarenone
 Graphite
 Manganese derivative
 Manganese oxide
 Oxide
 Thioctic acid
 Ubidecarenone
 Ubiquinone
 Accuracy
 Anodic stripping potentiometry
 Article
 Concentration (parameters)
 Cost
 Cyclic potentiometry
 Dietary supplement
 Electric capacitance
 Electrochemistry
 Enzyme assay
 Limit of detection
 Priority journal
 Quantitative analysis
 Screen printed graphene electrode
 Square wave anodic stripping potentiometry
 Analogs and derivatives
 Chemical structure
 Chemistry
 Electrochemical analysis
 Electrode
 Printing
 Electrochemical Techniques
 Electrodes
 Graphite
 Manganese Compounds
 Molecular Structure
 Oxides
 Printing
 Thioctic Acid
 Ubiquinone

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URI

https://hdl.handle.net/20.500.14740/5931

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Scopus: Year 1983-2021

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