Publication:
Low-fluence Q-switched Nd:YAG 1064-nm laser versus Q-switched Nd:YAG 532-nm laser in the treatment of hyperpigmented lips: a prospective, randomized, controlled, evaluator-blinded trial

2
0

Issued Date

2020

Resource Type

Article

File Type

application/pdf

ISSN

2688921

DOI

10.1007/s10103-019-02814-4

Other identifier(s)

2-s2.0-85067289844

Rights Holder(s)

Scopus

Bibliographic Citation

Lasers in Medical Science. Vol 35, No.1 (2020), p.165-171

Suggested Citation

Limpjaroenviriyakul N., Jurairattanaporn N., Kamanamool N., Rojhirunsakool S., Kanokrungsee S., Udompataikul M. Low-fluence Q-switched Nd:YAG 1064-nm laser versus Q-switched Nd:YAG 532-nm laser in the treatment of hyperpigmented lips: a prospective, randomized, controlled, evaluator-blinded trial. Lasers in Medical Science. Vol 35, No.1 (2020), p.165-171. doi:10.1007/s10103-019-02814-4 Retrieved from: https://hdl.handle.net/20.500.14740/4654

Title

Low-fluence Q-switched Nd:YAG 1064-nm laser versus Q-switched Nd:YAG 532-nm laser in the treatment of hyperpigmented lips: a prospective, randomized, controlled, evaluator-blinded trial

Author(s)

Limpjaroenviriyakul N.
 Jurairattanaporn N.
 Kamanamool N.
 Rojhirunsakool S.
 Kanokrungsee S.
 Udompataikul M.

Abstract

Lip hyperpigmentation is an esthetic problem. Clinical data from controlled comparative studies is insufficient to support the efficacy of laser treatments for hyperpigmented lips. This study is aimed to compare the efficacy of low-fluence Q-switched Nd:YAG 1064-nm laser (LFQS 1064-nm) versus Q-switched Nd:YAG 532-nm laser (QS 532-nm) for the treatment of hyperpigmented lips. A randomized, controlled, evaluator-blinded study was conducted in thirty subjects. They were randomized into 2 groups. The first group was treated with five treatment sessions with a 2-week interval of LFQS 1064-nm laser while the second group was treated with a single session of QS 532-nm laser. The evaluation was conducted at baseline, 2 weeks of each post treatment, and 4 weeks after the last treatment session. The efficacy was assessed by melanin index, Methuen colored plate, photographic evaluation, pain score, patient’s satisfaction, and patient’s Dermatology Life Quality Index. The adverse effects were also recorded. All patients attained throughout the study protocol. The most frequent fluence applied was 2.4 J/cm2 (2.2–2.5 J/cm2) and 2.0 J/cm2 (1.7–2.4 J/cm2) in the LFQS 1064-nm group and QS 532-nm group, respectively. The results of the QS 532-nm group showed greater percentage of melanin index reduction and better average mean of photographic evaluation percentage changes from the baseline than the LFQS 1064-nm group (p < 0.001 and p < 0.001, respectively). The adverse effects were less likely to occur in the LFQS 1064-nm group. Few cases of scale, hypopigmentation, bleb formation, postinflammatory hyperpigmentation, and labial edema occurred only in the QS 532-nm group. © 2019, Springer-Verlag London Ltd., part of Springer Nature.

Subject(s)

Adult
 Adverse outcome
 Article
 Bleb formation
 Burning sensation
 Clinical article
 Comparative effectiveness
 Controlled study
 Dermatology Life Quality Index
 Dry skin
 Edema
 Faces Pain Scale
 Female
 Human
 Hyperpigmentation
 Hypopigmentation
 Labial edema
 Lip disease
 Lip hyperpigmentation
 Low level laser therapy
 Male
 Medical photography
 Patient satisfaction
 Postinflammatory hyperpigmentation
 Priority journal
 Prospective study
 Purpura
 Randomized controlled trial
 Retrospective study
 Thailand
 Visual analog scale
 Drug therapy
 Hyperpigmentation
 Lip
 Metabolism
 Radiation response
 Solid state laser
 Treatment outcome
 Adult
 Female
 Humans
 Hyperpigmentation
 Lasers, Solid-State
 Lip
 Male
 Patient Satisfaction
 Prospective Studies
 Treatment Outcome

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URI

https://hdl.handle.net/20.500.14740/4654

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Scopus: Year 1983-2021

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