Publication:
A new amino amidine derivative from the wood-decaying fungus Xylaria cf. cubensis SWUF08-86

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Issued Date

2018

Resource Type

Article

File Type

application/pdf

ISSN

14786419

DOI

10.1080/14786419.2017.1405414

Other identifier(s)

2-s2.0-85034843617

Rights Holder(s)

มหาวิทยาลัยศรีนครินทรวิโรฒ

Bibliographic Citation

Natural Product Research. Vol 32, No.19 (2018), p.2260-2267

Suggested Citation

Sawadsitang S., Suwannasai N., Mongkolthanaruk W., Ahmadi P., Mccloskey S. A new amino amidine derivative from the wood-decaying fungus Xylaria cf. cubensis SWUF08-86. Natural Product Research. Vol 32, No.19 (2018), p.2260-2267. doi:10.1080/14786419.2017.1405414 Retrieved from: https://hdl.handle.net/20.500.14740/5825

Title

A new amino amidine derivative from the wood-decaying fungus Xylaria cf. cubensis SWUF08-86

Author(s)

Sawadsitang S.
 Suwannasai N.
 Mongkolthanaruk W.
 Ahmadi P.
 Mccloskey S.

Abstract

The secondary metabolites of Xylaria cf. cubensis SWUF08-86 fungus were investigated, and the chromatographic separation of the crude extracts yielded seventeen compounds. The structure elucidation by spectroscopic analysis including 1D and 2D NMR and the comparison of these data with literature, along with HREIMS spectrometry, revealed one new amino amidine derivative (1), together with five known simple cyclic dipeptide analogs, diketopiperazines (2–6) and eleven other known compounds, including one hemi-cycline (10), three aromatic derivatives (11–13), one sesquiterpene (14) and three sterols (15–17). The isolated compounds were screened for anticancer and anti-pathogenic bacterial and fungal activities. Based on this work, Xylaria cf. cubensis SWUF08-86 has proven to be a diverse secondary metabolites producer. © 2017, © 2017 Informa UK Limited, trading as Taylor & Francis Group.

Subject(s)

1h indole
 4 hydroxybenzoic acid
 Amidine
 Amino amidine derivative
 Amphotericin B
 Cycline
 Dipeptide
 Doxorubicin
 Ergosterol
 Ergosterol peroxide
 Piperazinedione
 Sesquiterpene
 Stellasterol
 Sterol
 Tamoxifen
 Unclassified drug
 Vancomycin
 Amidine
 Antifungal agent
 Antiinfective agent
 Antineoplastic agent
 Dipeptide
 Acinetobacter baumannii
 Alternaria brassicicola
 Antibacterial activity
 Antifungal activity
 Antineoplastic activity
 Article
 Chemical analysis
 Chemical structure
 Chromatography
 Controlled study
 Curvularia lunata
 Drug cytotoxicity
 Drug structure
 Enterococcus faecium
 Fungus
 Minimum inhibitory concentration
 Nonhuman
 Nuclear magnetic resonance
 Spectroscopy
 Thailand
 Xylaria cf. cubensis
 Chemistry
 Isolation and purification
 Metabolism
 Nuclear magnetic resonance spectroscopy
 Xylariales
 Amidines
 Anti-Bacterial Agents
 Antifungal Agents
 Antineoplastic Agents
 Dipeptides
 Magnetic Resonance Spectroscopy
 Molecular Structure
 Xylariales

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URI

https://hdl.handle.net/20.500.14740/5825

Collections

Scopus: Year 1983-2021

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