Publication:
Ovulation block by Pueraria mirifica: A study of its endocrinological effect in female monkeys

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Issued Date

2005

Resource Type

Article

File Type

application/pdf

ISSN

1355008X

Other identifier(s)

2-s2.0-23844558954

Rights Holder(s)

มหาวิทยาลัยศรีนครินทรวิโรฒ

Bibliographic Citation

Endocrine. Vol 26, No.1 (2005), p.33-39

Suggested Citation

Trisomboon H., Malaivijitnond S., Watanabe G., Taya K. Ovulation block by Pueraria mirifica: A study of its endocrinological effect in female monkeys. Endocrine. Vol 26, No.1 (2005), p.33-39. Retrieved from: https://hdl.handle.net/20.500.14740/6170

Title

Ovulation block by Pueraria mirifica: A study of its endocrinological effect in female monkeys

Author(s)

Trisomboon H.
 Malaivijitnond S.
 Watanabe G.
 Taya K.

Abstract

Pueraria mirifica (PM), a Thai herb containing phytoestrogens, may act as estrogen and disturb reproduction. To investigate the effect of PM on the menstrual cycle length and related hormones, nine adult female monkeys (Macaca fascicularis) were separated into three groups. Each group (n = 3) was fed with 10, 100, and 1000 mg/d of PM for three menstrual cycles. The menstrual cycle length increased significantly in mon-keys treated with PM-10 and PM-100 and disappeared completely in monkeys treated with PM-1000. Serum follicle stimulating hormone, luteinizing hormone, estradiol, progesterone, and ir-inhibin were lower during the treatment period in a dose-dependent manner. Changes in menstrual cycle length and the hormonal levels recovered during the post-treatment period only in monkeys treated with PM-10 and PM-100. PM greatly influences menstrual cycles and may suppress ovulation by lowering serum levels of gonadotropins. © 2005 by Humana Press Inc. All rights of any nature whatsoever reserved.

Subject(s)

Estradiol
 Follitropin
 Gonadotropin
 Inhibin
 Luteinizing hormone
 Phytoestrogen
 Progesterone
 Estradiol
 Follitropin
 Inhibin
 Luteinizing hormone
 Phytoestrogen
 Progesterone
 Animal experiment
 Article
 Dose response
 Estradiol blood level
 Feeding
 Female
 Follitropin blood level
 Gonadotropin blood level
 Herb
 Hormone blood level
 Hormone determination
 Luteinizing hormone blood level
 Macaca
 Menstrual cycle
 Monkey
 Nonhuman
 Ovulation inhibition
 Peuraria mirifica
 Priority journal
 Progesterone blood level
 Thailand
 Animal
 Blood
 Drug effect
 Menstrual cycle
 Pueraria
 Animals
 Estradiol
 Female
 Follicle Stimulating Hormone
 Inhibins
 Luteinizing Hormone
 Macaca fascicularis
 Menstrual Cycle
 Ovulation Inhibition
 Phytoestrogens
 Progesterone
 Pueraria

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URI

https://hdl.handle.net/20.500.14740/6170

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Scopus: Year 1983-2021

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