Publication: Zinc deficiency in children with dengue viral infection
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0
Issued Date
2019
Resource Type
File Type
application/pdf
ISSN
20367503
Other identifier(s)
2-s2.0-85064056666
Rights Holder(s)
Scopus
Bibliographic Citation
Pediatric Reports. Vol 11, No.1 (2019)
Suggested Citation
Rerksuppaphol L., Rerksuppaphol S. Zinc deficiency in children with dengue viral infection. Pediatric Reports. Vol 11, No.1 (2019). doi:10.4081/pr.2019.7386 Retrieved from: https://hdl.handle.net/20.500.14740/5581
Author(s)
Abstract
Zinc deficiency is highly prevalent in low-income countries, with dramatic consequences to child health, in particular by impairing the immune system resulting in infection. This cross-sectional study aimed to determine the prevalence of zinc deficiency in Thai children who were admitted to hospital with a diagnosis of the dengue viral infection. Standard cut-off values according to age, sex, time of blood collection, and fasting status were used to define zinc levels. 32 patients were included in the analysis: The mean age was 7.3 years, of whom 56.3% were males. 11 (34.4%) patients were diagnosed with dengue hemorrhagic fever and the remaining had dengue fever. The prevalence of zinc deficiency was 46.7%, with boys having a higher risk of zinc deficiency than girls (OR=7.3: 95%CI: 1.5-36.6). Fever duration and length of hospital stay were longer in children with zinc deficiency compared to those who had normal levels, albeit without a significant difference. The results of this study provide the rationale for larger studies that will better elucidate the relationship between zinc levels and the clinical outcomes of dengue disease. ©Copyright L. Rerksuppaphol and S. Rerksuppaphol, 2019.
Subject(s)
Alanine aminotransferase
Aspartate aminotransferase
Zinc
Alanine aminotransferase blood level
Article
Ascites
Aspartate aminotransferase level
Blood sampling
Body mass
Child
Child nutrition
Clinical article
Clinical feature
Cross-sectional study
Dengue
Dengue hemorrhagic fever
Disease duration
Female
Gastrointestinal hemorrhage
Headache
Human
Hypovolemic shock
Length of stay
Leukopenia
Male
Myalgia
Nausea and vomiting
Pleura effusion
Prevalence
Rash
School child
Thai (people)
Thrombocytopenia
Zinc blood level
Zinc deficiency
Aspartate aminotransferase
Zinc
Alanine aminotransferase blood level
Article
Ascites
Aspartate aminotransferase level
Blood sampling
Body mass
Child
Child nutrition
Clinical article
Clinical feature
Cross-sectional study
Dengue
Dengue hemorrhagic fever
Disease duration
Female
Gastrointestinal hemorrhage
Headache
Human
Hypovolemic shock
Length of stay
Leukopenia
Male
Myalgia
Nausea and vomiting
Pleura effusion
Prevalence
Rash
School child
Thai (people)
Thrombocytopenia
Zinc blood level
Zinc deficiency
