Publication: Prospective Evaluation of Correlation between Modified Reid’s Colposcopic Index (RCI) and Histopathology Result from Colposcopic Directed Biopsy
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Issued Date
2022
Resource Type
Language
eng
File Type
application/pdf
ISSN
1252208
Rights Holder(s)
Scopus
Bibliographic Citation
Journal of the Medical Association of Thailand. Vol 105, No. (2022), p.S68-S72
Suggested Citation
Rodpenpear N., Hamontri S. Prospective Evaluation of Correlation between Modified Reid’s Colposcopic Index (RCI) and Histopathology Result from Colposcopic Directed Biopsy. Journal of the Medical Association of Thailand. Vol 105, No. (2022), p.S68-S72. doi:10.35755/jmedassocthai.2022.S01.00025 Retrieved from: https://hdl.handle.net/20.500.14740/10276
Author(s)
Abstract
Objective: To evaluate correlation between Modified Reid Colposcopic Index and histopathology from colposcopic directed biopsy. Materials and Methods: At least atypical squamous cell of undetermined significance (ASC-US) according to the Bethesda classification 2001 was diagnosed in 60 eligible women. At the time of colposcopic examination, the four colposcopic criteria used are: 1) margin of cervical lesion, 2) color of acetowhite, 3) appearance of vessels on cervical lesion, and 4) location of the lesion. Each criterion was assigned in score between 0 to 2 and the summation of all four criteria made a total score ranging from 0 to 8. A score of less than or equal to 2 was classified as low grade lesion indicating of human papillomavirus (HPV) infection or cervical intraepithelial neoplasia (CIN)1. Intermediate grade was 3 to 5 indicating of CIN2 while, high grade lesion as a reflection of at least CIN3 is 6 to 8. Colposcopic directed biopsy on all lesions were performed for histopathologic examination. Results: The strength of agreement with Spearman rank correlation was 0.69. Sensitivity, specificity, positive and negative predictive value for differentiate high from low grade lesion were 91.7%, 66.7%, 64.7% and 92.3%, respectively. The overall accuracy of modified RCI after adjusted was 76.7%. Accuracy in a subgroup of low and high grade lesion were 92.3% and 64.7%, respectively. Conclusion: Modified Reid’s colposcopic index had a good positive correlation to cervical histopathology and also had high accuracy to differentiate low from high grade lesion. © JOURNAL OF THE MEDICAL ASSOCIATION OF THAILAND