Publication: Phytochemicals from root barks of garcinia cowa roxb. and antioxidant activity
2
0
Issued Date
2023-05-19
Resource Type
Language
eng
File Type
application/pdf
Access Rights
Open Access
Rights
ผลงานนี้เผยแพร่ภายใต้ สัญญาอนุญาตครีเอทีฟคอมมอนส์แบบ แสดงที่มา-ไม่ใช้เพื่อการค้า-ไม่ดัดแปลง 4.0 (CC BY-NC-ND 4.0)
Rights Holder(s)
Srinakharinwirot University
Suggested Citation
Pongsan Kornanan, พงศ์สันต์ กรอานันท์ (2023). Phytochemicals from root barks of garcinia cowa roxb. and antioxidant activity. Retrieved from: https://hdl.handle.net/20.500.14740/54281
Alternative Title(s)
พฤกษเคมีจากเปลือกรากชะมวงและฤทธิ์ ยับยั้งการเกิดออกซิเดชัน
Author(s)
Advisor(s)
Organization
Abstract
Garcinia cowa Roxb (Cha-muang) is one of the well-known medicinal plants belong to the Clusiaceae family. Many parts of G. cowa have been investigated for their interesting phytochemicals. In this work, the root barks of G. cowa were extracted with EtOAc and then with MeOH, and the extracts were fractionated and purified by column chromatographic techniques. From the MeOH extract obtained, four biflavonoids were identified as (+) volkensiflavone (BIF1), (+) morelloflavone (BIF2), (+) spicataside (BIF3), and (+) fukugiside (BIF4). The structure of all isolated compounds was elucidated by spectroscopic techniques, especially IR, 1D- and 2D- NMR including by comparison of their spectroscopic data with those reported in the literature. The antioxidant activity of the extracts and the isolated compounds were tested using DPPH radical scavenging assay. The isolated compounds BIF2 and BIF4 as well as the MeOH extract exhibited strong activity with IC50 values of 8.85, 19.65, and 47.40 μg/mL, respectively.
-
-
Degree Name
MASTER OF SCIENCE (M.Sc.)
Degree Discipline
Department Of Chemistry
Degree Grantor(s)
Srinakharinwirot University