Publication:
A transparency sheet-based colorimetric device for simple determination of calcium ions using induced aggregation of modified gold nanoparticles

0
0

Issued Date

2019

Resource Type

Article

File Type

application/pdf

ISSN

16616596

DOI

10.3390/ijms20122954

Other identifier(s)

2-s2.0-85068485265

Rights Holder(s)

Scopus

Bibliographic Citation

International Journal of Molecular Sciences. Vol 20, No.12 (2019)

Suggested Citation

Duenchay P., Chailapakul O., Siangproh W. A transparency sheet-based colorimetric device for simple determination of calcium ions using induced aggregation of modified gold nanoparticles. International Journal of Molecular Sciences. Vol 20, No.12 (2019). doi:10.3390/ijms20122954 Retrieved from: https://hdl.handle.net/20.500.14740/5307

Title

A transparency sheet-based colorimetric device for simple determination of calcium ions using induced aggregation of modified gold nanoparticles

Author(s)

Duenchay P.
 Chailapakul O.
 Siangproh W.

Abstract

A simple and novel transparency sheet-based colorimetric detection device using gold nanoparticles (AuNPs) modified by 4-Amino-6-hydroxy-2-mercaptopyrimidine monohydrate (AHMP) was fabricated and developed for the determination of calcium ions (Ca2+). The detection was based on a colorimetric reaction as a result of the aggregation of modified AuNPs induced by Ca2+ due to the ability to form strong electrostatic interactions between positively charged Ca2+ and negatively charged modified AuNPs. Probe solution changes color from red to blue in the presence of Ca2+ and can be observed by the naked eyes. To verify the complete self-assembly of the AHMP onto the AuNP surface, the modified AuNPs were characterized using ultraviolet–visible spectroscopy and zeta potential measurements. Under optimal conditions, a quantitative linearity was 10 to 100 ppm (R2 = 0.9877) with a detection limit of 3.05 ppm. The results obtained by the developed method were in good agreement with standard atomic absorption spectrometry (AAS) results and demonstrated that this method could reliably measure Ca2+. Overall, this novel alternative approach presents a low-cost, simple, sensitive, rapid, and promising device for the detection of Ca2+. © 2019 by the authors. Licensee MDPI, Basel, Switzerland.

Subject(s)

Calcium ion
 Gold nanoparticle
 Polypropylene
 Calcium
 Gold
 Ion
 Metal nanoparticle
 Analytical parameters
 Article
 Atomic absorption spectrometry
 Chemical modification
 Colorimetry
 Concentration (parameter)
 Cost effectiveness analysis
 Drug analysis
 Drug determination
 Electrochemical detection
 Limit of detection
 Limit of quantitation
 Measurement accuracy
 PH
 Process optimization
 Simulation
 Static electricity
 Stereoselectivity
 Surface plasmon resonance
 Ultraviolet visible spectrophotometry
 Urine sampling
 Validation process
 Zeta potential
 Chemistry
 Colorimetry
 Human
 Procedures
 Reproducibility
 Ultraviolet spectrophotometry
 Urinalysis
 Calcium
 Colorimetry
 Gold
 Humans
 Ions
 Metal Nanoparticles
 Reproducibility of Results
 Spectrophotometry, Ultraviolet
 Urinalysis

View online Resources

Research Projects

Organizational Units

Journal Issue

URI

https://hdl.handle.net/20.500.14740/5307

Collections

Scopus: Year 1983-2021

Endorsement

Review

Supplemented By

Referenced By