Publication:
Antimicrobial constituents and synergism effect of the essential oils from Cymbopogon citratus and Alpinia galanga

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Issued Date

2014

Resource Type

Article

File Type

application/pdf

ISSN

1934578X

DOI

10.1177/1934578x1400900237

Other identifier(s)

2-s2.0-84894429641

Rights Holder(s)

มหาวิทยาลัยศรีนครินทรวิโรฒ

Bibliographic Citation

Natural Product Communications. Vol 9, No.2 (2014), p.277-280

Suggested Citation

Tadtong S., Watthanachaiyingcharoen R., Kamkaen N. Antimicrobial constituents and synergism effect of the essential oils from Cymbopogon citratus and Alpinia galanga. Natural Product Communications. Vol 9, No.2 (2014), p.277-280. doi:10.1177/1934578x1400900237 Retrieved from: https://hdl.handle.net/20.500.14740/7119

Title

Antimicrobial constituents and synergism effect of the essential oils from Cymbopogon citratus and Alpinia galanga

Author(s)

Tadtong S.
 Watthanachaiyingcharoen R.
 Kamkaen N.

Abstract

From the fresh leaf sheathes of lemongrass (Cymbopogon citratus) and rhizomes of galanga (Alpinia galanga) light yellow and colorless oils, respectively, were obtained by hydrodistillation and microwave assisted extraction (MAE) in yields of 0.24% and 0.03%, and 0.11% and trace (w/w), respectively. By GC/MS analysis, five major constituents were identified in lemongrass oil, E-citral, Z-citral, β-myrcene, selina-6-en-4-ol, and cis-ocimene, and five in galanga oil, 1,8-cineole, phenol 4-(2-propenyl)- acetate, dl-limonene, α-pinene, and α-terpineol. Three major components of the combined lemongrass and galanga oils (ratio 7:3, 1:1, 3:7) were 1,8-cineole (46.3%, 31.5%, 19.3%), E-citral (12.8%, 22.7%, 32.8%) and Z-citral (8.5%, 15.2%, 21.6%). The MICs of lemongrass and galanga oils were: against Staphylococcus aureus 0.5% and 4%, v/v, against Pseudomonas aeruginosa 40% and >40%,v/v, against Streptococcus bovis 0.25% and 0.5%, v/v, and against Candida albicans 0.25% and 0.5%, v/v. Citral (from lemongrass oil) gave greater potentiation than 1,8-cineole (from galanga oil). The combination profiles of galanga oil with lemongrass oil (volume ratios 3:7, 1:1, and 7:3) were tested against the four pathogenic microorganisms. Synergistic activity was best noted for only one ratio (volume ratio 3:7) as the Σfic< 1 against all tested microorganisms. The present investigation provides evidenc that the utilization of two essential oils in combination should be assessed for synergistic antimicrobial activity in order to reduce their minimum effective dose.

Subject(s)

Amoxicillin
 Antiinfective agent
 Cineole
 Citral
 Clotrimazole
 Essential oil
 Limonene
 Myrcene
 Ocimene
 Phenol 4 (2 propenyl) acetate
 Pinene
 Selina 6 en 4 ol
 Terpineol
 Unclassified drug
 Alpinia galanga
 Antimicrobial activity
 Article
 Bactericidal activity
 Candida albicans
 Cell membrane
 Cymbopogon citratus
 Drug potentiation
 Extraction
 Hydrodistillation
 Infrared radiation
 Isolation procedure
 Leaf sheath
 Mass fragmentography
 Microbial growth
 Microwave assisted extraction
 Minimum bactericidal concentration
 Minimum inhibitory concentration
 Nonhuman
 Pseudomonas aeruginosa
 Rhizome
 Staphylococcus aureus
 Streptococcus bovis
 Alpinia
 Anti-Infective Agents
 Cymbopogon
 Drug Synergism
 Gas Chromatography-Mass Spectrometry
 Microbial Sensitivity Tests
 Oils, Volatile

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URI

https://hdl.handle.net/20.500.14740/7119

Collections

Scopus: Year 1983-2021

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