Publication:
In vitro studies on the relationship between the antioxidant activities of some berry extracts and their binding properties to serum albumin

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Issued Date

2014

Resource Type

Article

File Type

application/pdf

ISSN

2732289

DOI

10.1007/s12010-013-0712-2

Other identifier(s)

2-s2.0-84899472396

Rights Holder(s)

Scopus

Bibliographic Citation

Applied Biochemistry and Biotechnology. Vol 172, No.6 (2014), p.2849-2865

Suggested Citation

Namiesnik J., Vearasilp K., Nemirovski A., Leontowicz H., Leontowicz M., Pasko P., Martinez-Ayala A.L., González-Aguilar G.A., Suhaj M., Gorinstein S. In vitro studies on the relationship between the antioxidant activities of some berry extracts and their binding properties to serum albumin. Applied Biochemistry and Biotechnology. Vol 172, No.6 (2014), p.2849-2865. doi:10.1007/s12010-013-0712-2 Retrieved from: https://hdl.handle.net/20.500.14740/6454

Title

In vitro studies on the relationship between the antioxidant activities of some berry extracts and their binding properties to serum albumin

Author(s)

Namiesnik J.
 Vearasilp K.
 Nemirovski A.
 Leontowicz H.
 Leontowicz M.
 Pasko P.
 Martinez-Ayala A.L.
 González-Aguilar G.A.
 Suhaj M.
 Gorinstein S.

Abstract

The aim of this study was to investigate the possibility to use the bioactive components from cape gooseberry (Physalis peruviana), blueberry (Vaccinium corymbosum), and cranberry (Vaccinium macrocarpon) extracts as a novel source against oxidation in food supplementation. The quantitative analysis of bioactive compounds (polyphenols, flavonoids, flavanols, carotenoids, and chlorophyll) was based on radical scavenging spectrophometric assays and mass spectrometry. The total phenolic content was the highest (P < 0.05) in water extract of blueberries (46.6 ± 4.2 mg GAE/g DW). The highest antioxidant activities by 2,2-diphenyl-1-picrylhydrazyl radical scavenging assay and Cupric reducing antioxidant capacity were in water extracts of blueberries, showing 108.1 ± 7.2 and 131.1 ± 9.6 μMTE/g DW with correlation coefficients of 0.9918 and 0.9925, and by β-carotene linoleate assay at 80.1 ± 6.6 % with correlation coefficient of 0.9909, respectively. The water extracts of berries exhibited high binding properties with human serum albumin in comparison with quercetin. In conclusion, the bioactive compounds from a relatively new source of gooseberries in comparison with blueberries and cranberries have the potential as food supplementation for human health. The antioxidant and binding activities of berries depend on their bioactive compounds. © 2014 The Author(s).

Subject(s)

Agents
 Assays
 Binding energy
 Flavonoids
 Fruits
 Mass spectrometry
 Plants (botany)
 2 ,2-diphenyl-1-picrylhydrazyl
 Anti-oxidant activities
 Berries
 Binding properties
 Bioactive compounds
 Correlation coefficient
 Total phenolic content
 Vaccinium macrocarpon
 Extraction
 3 feruloylquinic acid
 4 coumaroyltartaric acid
 5 heptadecylresorcinol
 Acetic acid ethyl ester
 Apigenin
 Apigenin 7 glucuronide
 Beta carotene
 Blueberry extract
 Carotene
 Carotenoid
 Chlorogenic acid
 Chlorophyll a
 Chlorophyll b
 Cranberry extract
 Ether
 Flavanol derivative
 Flavonoid
 Human serum albumin
 Linoleic acid
 Physalis peruviana extract
 Piceatannol
 Piceatannol 3 o glucoside
 Plant extract
 Polyphenol
 Quercetin
 Quinic acid
 Tartaric acid
 Unclassified drug
 Unindexed drug
 Water
 Xanthophyll
 Antioxidant activity
 Antioxidant assay
 Article
 Binding affinity
 Blueberry
 Controlled study
 Cranberry
 Cupric reducing antioxidant capacity assay
 Diet supplementation
 DPPH radical scavenging assay
 Drug protein binding
 Fluorometry
 Gooseberry
 In vitro study
 Quantitative analysis
 Solvent extraction
 Grossulariaceae
 Physalis peruviana
 Vaccinium
 Vaccinium corymbosum
 Vaccinium macrocarpon
 Biphenyl Compounds
 Carotenoids
 Chlorophyll
 Dietary Supplements
 Flavonoids
 Free Radical Scavengers
 Fruit
 Humans
 Oxidation-Reduction
 Physalis
 Picrates
 Plant Extracts
 Polyphenols
 Protein Binding
 Serum Albumin
 Vaccinium
 Vaccinium macrocarpon

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URI

https://hdl.handle.net/20.500.14740/6454

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Scopus: Year 1983-2021

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