Publication:
Seizure threshold in ECT: II. Dose titration vs age and half age methods

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Issued Date

2000

Resource Type

Article

File Type

application/pdf

ISSN

1252208

Other identifier(s)

2-s2.0-0034151655

Rights Holder(s)

Scopus

Bibliographic Citation

Journal of the Medical Association of Thailand. Vol 83, No.3 (2000), p.278-283

Suggested Citation

Chanpattana W., Chakrabhand S., Techakasem P., Raksakietisak S. Seizure threshold in ECT: II. Dose titration vs age and half age methods. Journal of the Medical Association of Thailand. Vol 83, No.3 (2000), p.278-283. Retrieved from: https://hdl.handle.net/20.500.14740/6949

Title

Seizure threshold in ECT: II. Dose titration vs age and half age methods

Author(s)

Chanpattana W.
 Chakrabhand S.
 Techakasem P.
 Raksakietisak S.

Abstract

Seizure threshold determination is of crucial importance in optimizing electrical stimulus dosage at electroconvulsive therapy (ECT). We measured initial seizure threshold by means of Srinakharinwirot University titration schedule in 106 patients with schizophrenia or schizoaffective disorder, receiving bilateral ECT. Seizure threshold was approximately 106 milli-coulombs on average, and varied 5-fold across patients. Seizure threshold was directly related to age, but inversely related to motor seizure duration. Comparisons of stimulus charge were done with the Age and Half age methods. By using the Half age method, 68 per cent of patients would have seized at the first stimulation and resulted in a closer mean charge to dose-titration method than the Age method. The results may have important clinical implications for stimulus dosing strategy in ECT.

Subject(s)

Adolescent
 Adult
 Age
 Article
 Clinical trial
 Comparative study
 Electroconvulsive therapy
 Electrostimulation
 Female
 Human
 Male
 Methodology
 Middle aged
 Paranoid schizophrenia
 Perceptive threshold
 Probability
 Seizure
 Sensitivity and specificity
 Sex difference
 Adolescent
 Adult
 Age Factors
 Electric Stimulation
 Electroconvulsive Therapy
 Female
 Humans
 Male
 Middle Aged
 Probability
 Schizophrenia, Paranoid
 Seizures
 Sensitivity and Specificity
 Sensory Thresholds
 Sex Factors

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URI

https://hdl.handle.net/20.500.14740/6949

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Scopus: Year 1983-2021

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