Publication:
Blepharoclonus: Anatomical localization and etiological consideration

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Issued Date

2014

Resource Type

Article

File Type

application/pdf

ISSN

1252208

Other identifier(s)

2-s2.0-84914104898

Rights Holder(s)

Scopus

Bibliographic Citation

Journal of the Medical Association of Thailand. Vol 97, No.9 (2014), p.977-981

Suggested Citation

Methawasin K., Bhidayasiri R., Phanthumchinda K., Kaufman L. Blepharoclonus: Anatomical localization and etiological consideration. Journal of the Medical Association of Thailand. Vol 97, No.9 (2014), p.977-981. Retrieved from: https://hdl.handle.net/20.500.14740/6418

Title

Blepharoclonus: Anatomical localization and etiological consideration

Author(s)

Methawasin K.
 Bhidayasiri R.
 Phanthumchinda K.
 Kaufman L.

Abstract

Blepharoclonus refers to myoclonic rhythmic eyelid closure. This is an extremely rare abnormal movement of the eyelids. The symptom has an ill-defined anatomical localization and hypothesized etiologies are diverse. We describe a 42 year-old woman with known poorly controlled hypertension (HTN) who presented with a three-week history of ataxia, dysmetria, and uncontrolled eyelid twitching. The bilateral abnormal eyelid movement occurred during either eyelid closure or opening, and was compatible with blepharoclonus. MRI revealed multiple cerebral infarctions at red nucleus, dentate nucleus, and inferior olives. These foci are within Guillain-Mollaret’s triangle. The ataxia and dysmetria gradually improved within three weeks. While the blepharoclonus improved, it persisted after one year of follow-up. Our conclusion was one of HTN leading to a lacunar infarct that manifested partially as blepharoclonus. Due to the neuroimaging findings and clinical course, we propose that blepharoclonus may be a variant of palatal myoclonus and may be considered as another lacunar syndrome. © 2014, Medical Association of Thailand. All rights reserved.

Subject(s)

Acetylsalicylic acid
 Amlodipine
 Enalapril
 Adult
 Article
 Ataxia
 Blepharoclonus
 Blepharoclonus
 Blood pressure
 Brain infarction
 Brain ischemia
 Case report
 Cerebrospinal fluid analysis
 Cerebrovascular disease
 Computer assisted tomography
 Dentate nucleus
 Dysdiadokokinesia
 Dysmetria
 Eye disease
 Eyelid disease
 Eyelid reflex
 Female
 Follow up
 Human
 Hydration
 Hypertension
 Myoclonus
 Neuroimaging
 Neurologic disease
 Nose provocation test
 Nuclear magnetic resonance imaging
 Ophthalmoscopy
 Palate
 Slurred speech
 Visual acuity
 Blepharospasm
 Cerebral Infarction
 Complication
 Differential diagnosis
 Pathology
 Red nucleus
 Adult
 Blepharospasm
 Cerebral Infarction
 Diagnosis, Differential
 Female
 Humans
 Magnetic Resonance Imaging
 Red Nucleus

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https://hdl.handle.net/20.500.14740/6418

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Scopus: Year 1983-2021

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