Publication:
Maintenance ECT in Treatment-Resistant Schizophrenia

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Issued Date

2000

Resource Type

Article

File Type

application/pdf

ISSN

1252208

Other identifier(s)

2-s2.0-0034201252

Rights Holder(s)

มหาวิทยาลัยศรีนครินทรวิโรฒ

Bibliographic Citation

Journal of the Medical Association of Thailand. Vol 83, No.6 (2000), p.657-662

Suggested Citation

Chanpattana W. Maintenance ECT in Treatment-Resistant Schizophrenia. Journal of the Medical Association of Thailand. Vol 83, No.6 (2000), p.657-662. Retrieved from: https://hdl.handle.net/20.500.14740/7027

Title

Maintenance ECT in Treatment-Resistant Schizophrenia

Author(s)

Chanpattana W.

Abstract

Although electroconvulsive therapy (ECT) has been used to treat schizophrenia since its inception in 1938, its efficacy as long-term treatment is still controversial. A 2-Phase, prospective study has been conducted in 21 patients with schizophrenia. The duration of study was 1 year. Bilateral ECT combined with flupenthixol (18-24 mg/day) was used throughout. Brief Psychiatric Rating Scale (BPRS), Global Assessment of Functioning (GAF), and Mini-Mental-State Exam (MMSE) were used to measure the outcome. No patients suffered relapses. There were marked reductions in BPRS scores (73 per cent and 70 per cent), and increases in GAF scores (68 per cent and 91 per cent), at the end of Phases I and II, respectively. This study suggests a long-term efficacy of ECT combined with neuroleptic therapy in patients with schizophrenia.

Subject(s)

Flupentixol
 Neuroleptic agent
 Adolescent
 Adult
 Article
 Brief Psychiatric Rating Scale
 Clinical trial
 Drug resistance
 Electroconvulsive therapy
 Female
 Human
 Long term care
 Male
 Methodology
 Multimodality cancer therapy
 Phase 1 clinical trial
 Phase 2 clinical trial
 Prognosis
 Prospective study
 Schizophrenia
 Treatment failure
 Treatment outcome
 Adolescent
 Adult
 Antipsychotic Agents
 Brief Psychiatric Rating Scale
 Combined Modality Therapy
 Drug Resistance
 Electroconvulsive Therapy
 Female
 Flupenthixol
 Humans
 Long-Term Care
 Male
 Prognosis
 Prospective Studies
 Schizophrenia
 Treatment Failure
 Treatment Outcome

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URI

https://hdl.handle.net/20.500.14740/7027

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Scopus: Year 1983-2021

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