Publication: Nutri-jelly may improve quality of life and decrease tube feeding demand in head and neck cancer patients
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0
Issued Date
2015
Resource Type
File Type
application/pdf
ISSN
9414355
Other identifier(s)
2-s2.0-84939970068
Rights Holder(s)
Scopus
Bibliographic Citation
Supportive Care in Cancer. Vol 23, No.5 (2015), p.1421-1430
Suggested Citation
Trachootham D., Songkaew W., Hongsachum B., Wattana C., Changkluengdee N., Karapoch J., Thirdsuttironnapumi S., Meennuch E., Klaitong C., Sinthusek T., Lam-Ubol A. Nutri-jelly may improve quality of life and decrease tube feeding demand in head and neck cancer patients. Supportive Care in Cancer. Vol 23, No.5 (2015), p.1421-1430. doi:10.1007/s00520-014-2488-5 Retrieved from: https://hdl.handle.net/20.500.14740/6141
Abstract
Purpose: Eating difficulty is a critical and common problem in head and neck cancer patients undergoing radiotherapy (RT). It leads to poor quality of life and extensive tube feeding use. Nutri-jelly, a food gel with semisolid texture, water-releasing ability, and ready-to-eat by spoon, was recently developed to alleviate the trouble. However, its efficacy was unknown. This study investigated the potential effect of Nutri-jelly on health-related quality of life (HRQOL) and nasogastric tube feeding use. Methods: A prospective quasi-randomized patients-preference controlled trial was conducted in 74 head and neck cancer patients. Subjects in study and control groups (37 each) had similar baseline HRQOL and body mass index and undergone definitive radiotherapy (25–35 RT fractions, 5,000–7,000 cGy). Only study group received a 200-ml box of Nutri-jelly as daily supplement throughout radiotherapy. HRQOL was scored by validated questionnaires. The use of tube feeding was collected from medical records. Results: From 11 to 35 RT fractions, the study group maintained higher overall HRQOL score than that of control group (p < 0.0001). Multiple physiologic and psychological aspects of HRQOL especially swallowing difficulty and overall eating problems were significantly improved in study as compared to control group. Promisingly, the percentage of tube feeding use in study group (13.5 %) was dramatically lower than control group (48.6 %). Conclusions: Continuous supplementation of Nutri-jelly throughout radiotherapy may improve HRQOL and reduce tube feeding demand in head and neck cancer patients who preferred to take them. Nutri-jelly could be an alternative for head and neck cancer patients who have eating difficulty during radiotherapy. © 2014, The Author(s).
Subject(s)
Adult
Adverse effects
Aged
Controlled study
Diet supplementation
Digestive tract intubation
Eating
Enteric feeding
Female
Head and Neck Neoplasms
Human
Male
Middle aged
Pathophysiology
Procedures
Prospective study
Quality of life
Questionnaire
Randomized controlled trial
Adult
Aged
Dietary Supplements
Eating
Enteral Nutrition
Female
Head and Neck Neoplasms
Humans
Intubation, Gastrointestinal
Male
Middle Aged
Prospective Studies
Quality of Life
Radiotherapy
Surveys and Questionnaires
Adverse effects
Aged
Controlled study
Diet supplementation
Digestive tract intubation
Eating
Enteric feeding
Female
Head and Neck Neoplasms
Human
Male
Middle aged
Pathophysiology
Procedures
Prospective study
Quality of life
Questionnaire
Randomized controlled trial
Adult
Aged
Dietary Supplements
Eating
Enteral Nutrition
Female
Head and Neck Neoplasms
Humans
Intubation, Gastrointestinal
Male
Middle Aged
Prospective Studies
Quality of Life
Radiotherapy
Surveys and Questionnaires