Publication:
Predictive score for vesicoureteral reflux in children with a first febrile urinary tract infection

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Issued Date

2021

Resource Type

Article

Language

eng

File Type

application/pdf

ISSN

9198172

DOI

10.1111/iju.14515

Other identifier(s)

2-s2.0-85102778224

Rights Holder(s)

Scopus

Bibliographic Citation

International Journal of Urology. Vol 28, No.5 (2021), p.573-577

Suggested Citation

Lertdumrongluk K., Lertdumrongluk P. Predictive score for vesicoureteral reflux in children with a first febrile urinary tract infection. International Journal of Urology. Vol 28, No.5 (2021), p.573-577. doi:10.1111/iju.14515 Retrieved from: https://hdl.handle.net/20.500.14740/7815

Title

Predictive score for vesicoureteral reflux in children with a first febrile urinary tract infection

Author(s)

Lertdumrongluk K.
 Lertdumrongluk P.

Abstract

Objective: To develop a simple score for predicting vesicoureteral reflux after a first febrile urinary tract infection in children. Methods: A retrospective cohort study was conducted for a 12-year period (January 2008 to December 2019), including patients aged <72 months who underwent renal ultrasonography and voiding cystourethrography after a first febrile urinary tract infection. Patients with a history of antenatal hydronephrosis were excluded. The prediction model and score for vesicoureteral reflux were developed using multivariate logistic regression analysis. Results: Out of 260 patients in total (median age 4 months, 172 boys), 41 (16%) had vesicoureteral reflux. The score was based on four independent risk factors, including age >6 months (odds ratio 2.71, 95% confidence interval 1.27–5.76), presence of sepsis (odds ratio 3.44, 95% confidence interval 1.31–9.04), white blood cell count ≥15 000/mm3 (odds ratio 1.83, 95% confidence interval 0.88–3.8) and abnormal renal ultrasonography results (odds ratio 2.08, 95% confidence interval 1–4.31). A lower probability of vesicoureteral reflux (positive likelihood ratio = 0.66; P = 0.001) was found in the low-risk group (scores 0–2), whereas a higher probability of vesicoureteral reflux (positive likelihood ratio = 2.54; P = 0.001) was found in the high-risk group (scores 3–5). The predictive ability of the model was 70%. Conclusions: The scores developed based on the patient characteristics and renal ultrasonography are useful in predicting presence of vesicoureteral reflux after a first febrile urinary tract infection in children and could guide clinicians' decisions to perform additional imaging studies. © 2021 The Japanese Urological Association

Subject(s)

Age
 Article
 Child
 Cohort analysis
 Controlled study
 Echography
 Female
 Fever
 High risk population
 Human
 Human cell
 Hydronephrosis
 Infant
 Leukocyte count
 Low risk population
 Major clinical study
 Male
 Micturition cystourethrography
 Predictive score
 Predictive value
 Priority journal
 Retrospective study
 Risk factor
 Scoring system
 Sepsis
 Urinary tract infection
 Vesicoureteral reflux
 Aged
 Complication
 Diagnostic imaging
 Fever
 Kidney
 Pregnancy
 Urinary tract infection
 Vesicoureteral reflux
 Aged
 Child
 Female
 Fever
 Humans
 Infant
 Kidney
 Male
 Pregnancy
 Retrospective Studies
 Urinary Tract Infections
 Vesico-Ureteral Reflux

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URI

https://hdl.handle.net/20.500.14740/7815

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Scopus: Year 1983-2021

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