Publication: Measles seroprevalence in Thailand: Are adolescents and young adults at risk of measles
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Issued Date
2024-06-01
Resource Type
ISSN
00375675
eISSN
27375935
Scopus ID
2-s2.0-85137410136
Pubmed ID
35651287
Journal Title
Singapore Medical Journal
Volume
65
Issue
6
Start Page
340
End Page
347
Rights Holder(s)
SCOPUS
Bibliographic Citation
Singapore Medical Journal Vol.65 No.6 (2024) , 340-347
Suggested Citation
Takkinsatian P., Wannaphahoon K., Upapan P., Senawong S., Prommalikit O. Measles seroprevalence in Thailand: Are adolescents and young adults at risk of measles. Singapore Medical Journal Vol.65 No.6 (2024) , 340-347. 347. doi:10.11622/smedj.2022058 Retrieved from: https://hdl.handle.net/20.500.14740/20439
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Corresponding Author(s)
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Abstract
Introduction: During the last decade, measles has become an important re-emerging disease in Thailand. The objective of this study was to measure measles seroprevalence and its influencing factors so as to plan an improved vaccination programme. Methods: A total of 600 participants aged between 9 months and 50 years were divided into seven groups representing birth cohorts that experienced different measles vaccination policies. Participants' blood samples were obtained to measure measles immunoglobulin G (IgG) levels. Results: None of the participants in the age group of 9 months had measles IgG levels beyond a protective level. Participants in the age groups 2.5, 5-15, 16-29, 30-33, 34-40 and 41-50 years had 82% (95% confidence interval [CI] 73.3-90.7), 50% (95% CI 36.1-63.9), 52% (95% CI 42.3-62.7), 70% (95% CI 61.1-78.9), 88.8% (95% CI 84.1-93.5) and 98.8% (95% CI 96.4-100.0) measles seropositivity, respectively. The study did not find any significant factors affecting measles seropositivity. Conclusion: Individuals aged 15-34 years are vulnerable to measles infections. Supplementary vaccination should be encouraged in special situations, including postexposure prophylaxis for young adults during an outbreak and for high-risk occupations such as healthcare personnel.