Publication:
Ranitidine-enhanced 99m technetium pertechnetate imaging in children improves the sensitivity of identifying heterotopic gastric mucosa in Meckel's diverticulum

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Issued Date

2004

Resource Type

Review

File Type

application/pdf

ISSN

1790358

DOI

10.1007/s00383-004-1189-4

Other identifier(s)

2-s2.0-3242690710

Rights Holder(s)

มหาวิทยาลัยศรีนครินทรวิโรฒ

Bibliographic Citation

Pediatric Surgery International. Vol 20, No.5 (2004), p.323-325

Suggested Citation

Rerksuppaphol S., Hutson J.M., Oliver M.R. Ranitidine-enhanced 99m technetium pertechnetate imaging in children improves the sensitivity of identifying heterotopic gastric mucosa in Meckel's diverticulum. Pediatric Surgery International. Vol 20, No.5 (2004), p.323-325. doi:10.1007/s00383-004-1189-4 Retrieved from: https://hdl.handle.net/20.500.14740/6480

Title

Ranitidine-enhanced 99m technetium pertechnetate imaging in children improves the sensitivity of identifying heterotopic gastric mucosa in Meckel's diverticulum

Author(s)

Rerksuppaphol S.
 Hutson J.M.
 Oliver M.R.

Abstract

Meckel's diverticulum is the most common congenital gastrointestinal anomaly. 99m Technetium pertechnetate imaging (Meckel's scan) is the best noninvasive method used to diagnose this condition when heterotopic gastric mucosa (HGM) is present. Although cimetidine enhancement has been shown to improve sensitivity of the Meckel's scan, ranitidine enhancement has also been advocated; however, this recommendation is based on unpublished data. Thirty-seven children with confirmed Meckel's diverticulum were reviewed retrospectively. Of eight children with HGM in the Meckel's diverticulum who presented with profuse rectal bleeding and underwent the conventional Meckel's scan, three of them (37.5%) had a false negative study. Ranitidine, when administered either intravenously or orally for 24 h prior to the Meckel's scan, enhanced the sensitivity of this test to 87.5% in our patient cohort.

Subject(s)

Cimetidine
 Pertechnetic acid tc 99m
 Ranitidine
 Diagnostic agent
 Histamine H2 receptor antagonist
 Radiopharmaceutical agent
 Ranitidine
 Adolescent
 Child
 Clinical article
 Contrast enhancement
 Diagnostic accuracy
 Drug safety
 Female
 Human
 Infant
 Male
 Meckel diverticulum
 Priority journal
 Rectum hemorrhage
 Retrospective study
 Review
 Scintiscanning
 Stomach mucosa
 Article
 Choristoma
 Ileum disease
 Image enhancement
 Meckel diverticulum
 Newborn
 Preschool child
 Sensitivity and specificity
 Adolescent
 Child
 Child, Preschool
 Choristoma
 Female
 Gastric Mucosa
 Histamine H2 Antagonists
 Humans
 Ileal Diseases
 Image Enhancement
 Infant
 Infant, Newborn
 Male
 Meckel Diverticulum
 Radiopharmaceuticals
 Ranitidine
 Retrospective Studies
 Sensitivity and Specificity
 Sodium Pertechnetate Tc 99m

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URI

https://hdl.handle.net/20.500.14740/6480

Collections

Scopus: Year 1983-2021

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Review

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