Publication: Physico-chemical and in vitro cytotoxic properties of alginate/soy protein isolated scaffolds for tissue engineering
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Issued Date
2017
Resource Type
File Type
application/pdf
ISSN
10139826
Other identifier(s)
2-s2.0-85034039500
Rights Holder(s)
มหาวิทยาลัยศรีนครินทรวิโรฒ
Bibliographic Citation
Key Engineering Materials. Vol 757 KEM, (2017), p.46-51
Suggested Citation
Nooeaid P., Chuysinuan P., Techasakul S., Lirdprapamongkol K., Svasti J. Physico-chemical and in vitro cytotoxic properties of alginate/soy protein isolated scaffolds for tissue engineering. Key Engineering Materials. Vol 757 KEM, (2017), p.46-51. doi:10.4028/www.scientific.net/KEM.757.46 Retrieved from: https://hdl.handle.net/20.500.14740/4690
Abstract
Three-dimensional (3D) porous alginate/soy protein isolated (Alg/SPI) tissue engineering scaffolds were achieved by freeze-drying. The physico-chemical attributes of the scaffolds including morphology, chemical structure, mechanical properties and in vitro cytotoxicity were investigated for different SPI blends. Results indicated that increasing SPI content to 40 wt% in the blends resulted in the partial existence of closed pores and reduced pore size. The mechanical values of the scaffolds under compression also reduced with increasing SPI in the blends. The addition of SPI did not significantly enhance the cell viability of the scaffolds investigated for in vitro culture with human fibroblasts, which remained in the high (90 - 100%) range. Results demonstrated that Alg/SPI scaffolds have potential for use as tissue engineering scaffolds. © 2017 Trans Tech Publications, Switzerland.