Publication: Preparation and characterization of electrospun polyacrylonitrile fiber mats containing Garcinia mangostana
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Issued Date
2018
Resource Type
File Type
application/pdf
ISSN
1700839
Other identifier(s)
2-s2.0-85021094125
Rights Holder(s)
Scopus
Bibliographic Citation
Polymer Bulletin. Vol 75, No.3 (2018), p.1311-1327
Suggested Citation
Chuysinuan P., Techasakul S., Suksamrarn S., Wetprasit N., Hongmanee P., Supaphol P. Preparation and characterization of electrospun polyacrylonitrile fiber mats containing Garcinia mangostana. Polymer Bulletin. Vol 75, No.3 (2018), p.1311-1327. doi:10.1007/s00289-017-2087-y Retrieved from: https://hdl.handle.net/20.500.14740/3694
Abstract
Garcinia mangostana-loaded electrospun polyacrylonitrile (PAN) fiber mats with antibacterial and anti-tuberculosis properties were fabricated from PAN solution containing G. mangostana extract in dimethylformamide. 10% PAN solution was mixed with G. mangostana in amounts of 10, 15, 20, and 30 wt% based on the weight of PAN powder used in the experiment. The PAN solutions were processed using the electrospinning process. Both untreated (neat) and G. mangostana-loaded PAN fibers were smooth in appearance, and the average diameter of samples was ~215 and ~245 nm, respectively. Morphologies, release characteristics, antimicrobial efficiencies against Staphylococcus aureus, Methicillin-resistant S. aureus (MRSA), Staphylococcus epidermidis, Streptococcus agalactiae, Streptococcus pyogenes, and anti-tuberculosis properties of the neat electrospun and 10–30% G. mangostana-loaded e-spun fiber mats were investigated. In vitro release studies of G. mangostana from e-spun PAN fiber mats were determined using the total immersion method in acetate buffer and phosphate buffer solutions containing Tween 80 and methanol. The cumulative released amount of G. mangostana from the samples proportionally increased with the increase of G. mangostana incorporated in the spinning solutions. This study demonstrated a convenient procedure with the potential to develop the antimicrobial and anti-tuberculosis properties of electrospun fibrous membranes containing G. mangostana, which are beneficial in filtration applications for respirators, face masks, and air-conditioning filters. © 2017, Springer-Verlag GmbH Germany.
Subject(s)
Bacteria
Electrospinning
Fibers
Fibrous membranes
Filtration
Microfiltration
Microorganisms
Polyacrylonitriles
Electrospinning process
Electrospun fibrous membranes
Garcinia mangostana
Phosphate buffer solutions
Polyacrylonitrile fiber
Release characteristics
Staphylococcus epidermidis
Streptococcus agalactiae
Spinning (fibers)
Electrospinning
Fibers
Fibrous membranes
Filtration
Microfiltration
Microorganisms
Polyacrylonitriles
Electrospinning process
Electrospun fibrous membranes
Garcinia mangostana
Phosphate buffer solutions
Polyacrylonitrile fiber
Release characteristics
Staphylococcus epidermidis
Streptococcus agalactiae
Spinning (fibers)