Publication:
Clinical manifestations of early childhood dengue virus infection in Thailand

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Issued Date

2021

Resource Type

Article

Language

eng

File Type

application/pdf

ISSN

3005283

Other identifier(s)

2-s2.0-85121150916

Rights Holder(s)

มหาวิทยาลัยศรีนครินทรวิโรฒ

Bibliographic Citation

Medical Journal of Malaysia. Vol 76, No.6 (2021), p.853-856

Suggested Citation

Prommalikit O., Thisyakorn U., Thisyakorn C. Clinical manifestations of early childhood dengue virus infection in Thailand. Medical Journal of Malaysia. Vol 76, No.6 (2021), p.853-856. Retrieved from: https://hdl.handle.net/20.500.14740/8135

Title

Clinical manifestations of early childhood dengue virus infection in Thailand

Author(s)

Prommalikit O.
 Thisyakorn U.
 Thisyakorn C.

Abstract

Introduction: Clinical manifestations of dengue infection has a wide spectrum. This study aimed to describe and compare the clinical aspects of dengue infection in early childhood and those in older children. Materials and Methods: All dengue patients hospitalised at King Chulalongkorn Memorial Hospital, Bangkok, Thailand during 1987-2008 and aged 0-15 years were included. All parameters were compared between patients in two groups: aged 0-2 years and >2-15 years. Results: Of the 2,221 children who were diagnosed with dengue, 179 were children aged 0-2 years compared with 2,042 children aged >2-15 years. The early childhood group presented significantly more frequently with hepatomegaly, drowsiness, diarrhoea, rash, convulsions, splenomegaly, and unusual manifestations. Dengue fever (DF) was more common in the early childhood group and dengue haemorrhagic fever (DHF) was less common. The mortality rate of the early childhood group was 1.67%, which was significantly higher than that of the comparative group. Approximately 65% of study subjects were serologically proven to have primary infection, compared to 9.8% of older children. Conclusions: Clinical manifestations of dengue infection in early childhood are different in some aspects from those of dengue infection in older children, and mortality is higher. To effectively prevent dengue infection morbidity and mortality in children, it is essential that clinicians correctly recognize and diagnose dengue infection, particularly in early childhood. © 2021, Malaysian Medical Association. All rights reserved.

Subject(s)

Abdominal pain
 Adolescent
 Article
 Bleeding
 Child
 Clinical article
 Common cold
 Comparative study
 Controlled study
 Convulsion
 Dengue
 Dengue hemorrhagic fever
 Dengue virus
 Diarrhea
 Drowsiness
 Enzyme linked immunosorbent assay
 Female
 Hemagglutination inhibition test
 Hepatomegaly
 Human
 Immune adherence
 Infant
 Male
 Medical record
 Mortality
 Newborn
 Platelet count
 Polymorphonuclear cell
 Positive tourniquet test
 Preschool child
 Primary infection
 Rare disease
 Rash
 Retrospective study
 School child
 Secondary infection
 Skin manifestation
 Splenomegaly
 Thailand
 Vomiting
 World Health Organization

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URI

https://hdl.handle.net/20.500.14740/8135

Collections

Scopus: Year 1983-2021

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