Publication: Vessel tortuosity cutoff values using the modified Roptool may predict need for treatment in retinopathy of prematurity
0
0
Issued Date
2019
Resource Type
File Type
application/pdf
ISSN
23258160
Other identifier(s)
2-s2.0-85065081998
Rights Holder(s)
Scopus
Bibliographic Citation
Ophthalmic Surgery Lasers and Imaging Retina. Vol 50, No.4 (2019), p.215-220
Suggested Citation
Lertjirachai I., Stem M.S., Moysidis S.N., Koulisis N., Capone A., Jr., Drenser K.A., Trese M.T. Vessel tortuosity cutoff values using the modified Roptool may predict need for treatment in retinopathy of prematurity. Ophthalmic Surgery Lasers and Imaging Retina. Vol 50, No.4 (2019), p.215-220. doi:10.3928/23258160-20190401-03 Retrieved from: https://hdl.handle.net/20.500.14740/5661
Abstract
BACKGROUND AND OBJECTIVE: To quantify vessel tortuosity among infants with retinopathy of prematurity (ROP). PATIENTS AND METHODS: This was a retrospective study including 61 RetCam images from 33 infants. The laser treatment (LT) group included 17 infants who underwent laser for ROP. The no-treatment (NT) group included 16 infants. The modified ROPtool was used to calculate mean vessel tortuosity (MVT) and highest vessel tortuosity (HVT) for the participants and for the standard plus disease photograph from the Early Treatment for Retinopathy of Prematurity (ETROP) study. RESULTS: The median MVT was 1.226 versus 1.056 for the LT and NT groups, respectively (P < .001). The median HVT was 1.346 versus 1.088 (P < .001). An MVT of 1.124 was 96.7% sensitive and 100% specific for identifying infants with treatment-requiring ROP. Both MVT and HVT cutoff values correctly captured plus disease in the standard ETROP trial photograph. CONCLUSION: The modified ROPtool can be used to identify infants who have treatment-requiring ROP with a high level of sensitivity and specificity. © 2019 Slack Incorporated. All rights reserved.
Subject(s)
Arteriole
Article
Clinical article
Controlled study
Data analysis software
Diagnostic accuracy
Female
Highest vessel tortuosity
Human
Image analysis
Infant
Low level laser therapy
Male
Mean vessel tortuosity
Medical photography
Prediction
Prematurity
Priority journal
Quantitative analysis
Receiver operating characteristic
Reference value
Retina blood vessel
Retinal vessel tortuosity
Retrolental fibroplasia
Retrospective study
Sensitivity and specificity
Statistical significance
Treatment indication
Venule
Computer assisted diagnosis
Follow up
Newborn
Pathology
Predictive value
Procedures
Reproducibility
Retrolental fibroplasia
Diagnosis, Computer-Assisted
Female
Follow-Up Studies
Humans
Infant, Newborn
Laser Therapy
Male
Predictive Value of Tests
Reproducibility of Results
Retinal Vessels
Retinopathy of Prematurity
Retrospective Studies
ROC Curve
Article
Clinical article
Controlled study
Data analysis software
Diagnostic accuracy
Female
Highest vessel tortuosity
Human
Image analysis
Infant
Low level laser therapy
Male
Mean vessel tortuosity
Medical photography
Prediction
Prematurity
Priority journal
Quantitative analysis
Receiver operating characteristic
Reference value
Retina blood vessel
Retinal vessel tortuosity
Retrolental fibroplasia
Retrospective study
Sensitivity and specificity
Statistical significance
Treatment indication
Venule
Computer assisted diagnosis
Follow up
Newborn
Pathology
Predictive value
Procedures
Reproducibility
Retrolental fibroplasia
Diagnosis, Computer-Assisted
Female
Follow-Up Studies
Humans
Infant, Newborn
Laser Therapy
Male
Predictive Value of Tests
Reproducibility of Results
Retinal Vessels
Retinopathy of Prematurity
Retrospective Studies
ROC Curve