Publication:
Non-enzymatic electrochemical detection of glucose with a disposable paper-based sensor using a cobalt phthalocyanine–ionic liquid–graphene composite

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Issued Date

2018

Resource Type

Article

File Type

application/pdf

ISSN

9565663

DOI

10.1016/j.bios.2017.11.015

Other identifier(s)

2-s2.0-85033400550

Rights Holder(s)

Scopus

Bibliographic Citation

Biosensors and Bioelectronics. Vol 102, (2018), p.113-120

Suggested Citation

Chaiyo S., Mehmeti E., Siangproh W., Hoang T.L., Nguyen H.P., Chailapakul O., Kalcher K. Non-enzymatic electrochemical detection of glucose with a disposable paper-based sensor using a cobalt phthalocyanine–ionic liquid–graphene composite. Biosensors and Bioelectronics. Vol 102, (2018), p.113-120. doi:10.1016/j.bios.2017.11.015 Retrieved from: https://hdl.handle.net/20.500.14740/5895

Title

Non-enzymatic electrochemical detection of glucose with a disposable paper-based sensor using a cobalt phthalocyanine–ionic liquid–graphene composite

Author(s)

Chaiyo S.
 Mehmeti E.
 Siangproh W.
 Hoang T.L.
 Nguyen H.P.
 Chailapakul O.
 Kalcher K.

Abstract

We introduce for the first time a paper-based analytical device (PAD) for the non-enzymatic detection of glucose by modifying a screen-printed carbon electrode with cobalt phthalocyanine, graphene and an ionic liquid (CoPc/G/IL/SPCE). The modifying composite was characterized by UV–visible spectroscopy, energy dispersive X-ray spectroscopy (EDX), transmission electron microscopy (TEM) and scanning electron microscopy (SEM). The disposable devices show excellent conductivity and fast electron transfer kinetics. The results demonstrated that the modified electrode on PADs had excellent electrocatalytic activity towards the oxidation of glucose with NaOH as supporting electrolyte (0.1 M). The oxidation potential of glucose was negatively shifted to 0.64 V vs. the screen-printed carbon pseudo-reference electrode. The paper-based sensor comprised a wide linear concentration range for glucose, from 0.01 to 1.3 mM and 1.3–5.0 mM for low and high concentration of glucose assay, respectively, with a detection limit of 0.67 µM (S/N = 3). Additionally, the PADs were applied to quantify glucose in honey, white wine and human serum. The disposable, efficient, sensitive and low-cost non-enzymatic PAD has great potential for the development of point-of-care testing (POCT) devices that can be applied in healthcare monitoring. © 2017 Elsevier B.V.

Subject(s)

Analytic equipment
 Chemical detection
 Cobalt
 Electrochemical electrodes
 Electrolytes
 Energy dispersive spectroscopy
 Glucose sensors
 Graphene
 Graphene devices
 High resolution transmission electron microscopy
 Ionic liquids
 Scanning electron microscopy
 Sodium hydroxide
 Transmission electron microscopy
 Cobalt phthalocyanine
 Electrocatalytic activity
 ELectrochemical detection
 Energy dispersive X ray spectroscopy
 Non-enzymatic glucose sensors
 Paper-based analytical devices
 Pseudo reference electrodes
 Screen-printed carbon electrodes
 Glucose
 Carbon
 Cobalt
 Electrolyte
 Glucose
 Graphene
 Ionic liquid
 Phthalocyanine
 Sodium hydroxide
 Cobalt phthalocyanine
 Glucose
 Graphite
 Indole derivative
 Ionic liquid
 Organometallic compound
 Article
 Catalysis
 Conductance
 Controlled study
 Cost
 Electrochemical detection
 Electron transport
 Energy dispersive X ray spectroscopy
 Fast electron radiation
 Glucose assay
 Glucose oxidation
 Glycation
 Honey
 Human
 Limit of detection
 Oxidation reduction potential
 Point of care testing
 Scanning electron microscopy
 Sensitivity and specificity
 Serum
 Transmission electron microscopy
 Ultraviolet spectroscopy
 Wine
 Analysis
 Chemistry
 Devices
 Electrochemical analysis
 Electrode
 Equipment design
 Evaluation study
 Food analysis
 Genetic procedures
 Glucose blood level
 Paper
 Biosensing Techniques
 Blood Glucose
 Electrochemical Techniques
 Electrodes
 Equipment Design
 Food Analysis
 Glucose
 Graphite
 Honey
 Humans
 Indoles
 Ionic Liquids
 Limit of Detection
 Organometallic Compounds
 Paper
 Wine

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URI

https://hdl.handle.net/20.500.14740/5895

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Scopus: Year 1983-2021

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