Publication:
The association of metabolic parameters with gout in thai adults

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Issued Date

2021

Resource Type

Article

Language

eng

File Type

application/pdf

ISSN

1252208

DOI

10.35755/jmedassocthai.2021.S03.00011

Other identifier(s)

2-s2.0-85115991787

Rights Holder(s)

Scopus

Bibliographic Citation

Journal of the Medical Association of Thailand. Vol 104, No.9 (2021), p.S23-S30

Suggested Citation

Khuancharee K., Wannaiampikul S., Sangsawangchot P., Tanunyutthawongse C. The association of metabolic parameters with gout in thai adults. Journal of the Medical Association of Thailand. Vol 104, No.9 (2021), p.S23-S30. doi:10.35755/jmedassocthai.2021.S03.00011 Retrieved from: https://hdl.handle.net/20.500.14740/4022

Title

The association of metabolic parameters with gout in thai adults

Author(s)

Khuancharee K.
 Wannaiampikul S.
 Sangsawangchot P.
 Tanunyutthawongse C.

Abstract

Background: Despite the close relationships between metabolic parameters and gout, there is no data concerning this relation in the Thai adult population. Objective: The aim of the present study was to determine the association between metabolic parameters and gout. Materials and Methods: We conducted a 1:2 case-control study that included 90 gout patients as the case and 180 non-gout patients as the control group. Gout was defined as Rome criteria and confirmed by a rheumatologist. Diagnosis of metabolic syndrome was based on ATP III criteria. Multivariate unconditional logistic regression analysis was used to analyze the data and presented in terms of adjusted odds ratio (aOR) and 95% confidence interval (95% CI). Results: Our results revealed that gout was significantly associated with age increase every 10 years, men, high fasting blood glucose (FBG), and high blood pressure (BP). The aOR and 95% CI were 1.64 (1.29 to 2.07), 14.51 (6.17 to 34.27), 2.16 (1.08 to 4.46), and 2.01 (1.88 to 4.62), respectively. In addition, obesity with metabolic syndrome participants had an increased risk of gout (aOR = 2.78, 95% CI = 1.16 to 6.67). Conclusion: The present study indicates a significant association between gout and older age, men, high fasting blood glucose, and high blood pressure among Thai adults. Furthermore, a greater body mass index with metabolic syndrome increases the risk of gout. Subjects with these risk factors should be provided with appropriate management and treatment options. © JOURNAL OF THE MEDICAL ASSOCIATION OF THAILAND, 2021.

Subject(s)

Glucose
 High density lipoprotein cholesterol
 Low density lipoprotein cholesterol
 Triacylglycerol
 Uric acid
 Adult
 Article
 Blood sampling
 Body mass
 Case control study
 Cholesterol blood level
 Controlled study
 Diabetes mellitus
 Diastolic blood pressure
 Dyslipidemia
 Female
 Glucose blood level
 Gout
 Human
 Hypertension
 Hypertriglyceridemia
 Major clinical study
 Male
 Metabolic parameters
 Metabolic syndrome X
 Obesity
 Rheumatologist
 Systolic blood pressure
 Triacylglycerol blood level
 Uric acid blood level

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URI

https://hdl.handle.net/20.500.14740/4022

Collections

Scopus: Year 1983-2021

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