Publication: The comparative study of efficacy between cream containing spent grain wax, shea butter, Argania spinosa kernel oil, tapioca starch, and 1% hydrocortisone cream in the treatment of intertrigo
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0
Issued Date
2021
Resource Type
Language
eng
File Type
application/pdf
ISSN
1252208
Other identifier(s)
2-s2.0-85104642872
Rights Holder(s)
Scopus
Bibliographic Citation
Journal of the Medical Association of Thailand. Vol 104, No.4 (2021), p.565-570
Suggested Citation
Rodjanont A., Kamanamool N., Cheyasak N., Asawutmangkul C.S., Udompataikul M. The comparative study of efficacy between cream containing spent grain wax, shea butter, Argania spinosa kernel oil, tapioca starch, and 1% hydrocortisone cream in the treatment of intertrigo. Journal of the Medical Association of Thailand. Vol 104, No.4 (2021), p.565-570. doi:10.35755/jmedassocthai.2021.04.11643 Retrieved from: https://hdl.handle.net/20.500.14740/7838
Abstract
Background: Intertrigo is a common skin problem. Although there was no standard treatment due to few clinical studies, topical corticosteroids, and drying agents such as talcum are usually used to treat intertrigo, and the side effects of these agents should be monitoring. Objective: To compare the efficacy between cream containing spent grain wax, shea butter, Argania spinosa kernel oil, Tapioca starch, and 1% hydrocortisone cream for the treatment and prevention of intertrigo. Materials and Methods: Fifty-eight lesions from 18 intertrigo patients were randomized into two groups, HCC group, which is the 1% hydrocortisone cream and STIMU-TEX AS group, which is the combination cream of spent grain wax, shea butter, Argania spinosa kernel oil, and tapioca starch. The evaluations were performed at baseline, the first week, the second week, and the fourth week via scoring of skin redness, pruritus, excoriation, Dermatology Life Quality Index (DLQI), and patient satisfaction. The adverse events were also recorded. Results: All participants completed the protocol. At the end of the study, 27 of 29 lesions were completely cured in the HCC group, and 25 of 29 lesions cured in the STIMU-TEX AS group. Although the number of complete remissions of the STIMU-TEX AS group was inferior to the HCC group, it was not statistically significant. There was no relapse within two weeks after completing the treatment. Conclusion: The outcomes showed no statistically significant difference between both groups; thus, the cream may be considered as an alternative treatment and prevention of intertrigo. © Journal of the Medical Association of Thailand | 2021
Subject(s)
Grain wax
Hydrocortisone
Palm kernel oil
Skin cream
Starch
Talc
Tapioca starch
Unclassified drug
Wax
Adult
Application site excoriation
Article
Butter
Comparative study
Controlled study
Cream
Demography
Dermatology Life Quality Index
Double blind procedure
Drug efficacy
Erythema
Female
Human
Intertrigo
Major clinical study
Male
Numeric rating scale
Patient satisfaction
Pruritus
Questionnaire
Randomized controlled trial
Remission
Severity Scoring of Atopic Dermatitis
Shea butter
Skin defect
Treatment outcome
Visual analog scale
Young adult
Hydrocortisone
Palm kernel oil
Skin cream
Starch
Talc
Tapioca starch
Unclassified drug
Wax
Adult
Application site excoriation
Article
Butter
Comparative study
Controlled study
Cream
Demography
Dermatology Life Quality Index
Double blind procedure
Drug efficacy
Erythema
Female
Human
Intertrigo
Major clinical study
Male
Numeric rating scale
Patient satisfaction
Pruritus
Questionnaire
Randomized controlled trial
Remission
Severity Scoring of Atopic Dermatitis
Shea butter
Skin defect
Treatment outcome
Visual analog scale
Young adult