Publication: Synthesis of PANI/hematite/PB hybrid nanocomposites and fabrication as screen printed paper based sensors for cholesterol detection
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Issued Date
2016
Resource Type
File Type
application/pdf
ISSN
17599660
Other identifier(s)
2-s2.0-84996868209
Rights Holder(s)
มหาวิทยาลัยศรีนครินทรวิโรฒ
Bibliographic Citation
Analytical Methods. Vol 8, No.45 (2016), p.8049-8058
Suggested Citation
Maluin F.N., Sharifah M., Rattanarat P., Siangproh W., Chailapakul O., Issam A.M., Manan N.S.A. Synthesis of PANI/hematite/PB hybrid nanocomposites and fabrication as screen printed paper based sensors for cholesterol detection. Analytical Methods. Vol 8, No.45 (2016), p.8049-8058. doi:10.1039/c6ay02478e Retrieved from: https://hdl.handle.net/20.500.14740/4877
Abstract
In this work, the composites of polyaniline/nano-hematite (α-Fe2O3)/Prussian Blue (PB) were successfully synthesized via a sonochemical method. This nanocomposite (PB/CPANI) has been used for the modification of paper-based sensors for cholesterol detection. The electrochemical studies of this nanocomposite showed a well-defined cyclic voltammogram for hydrogen peroxide (H2O2) with a remarkable electrochemical sensitivity. This nanocomposite modified paper-based electrode also showed excellent electrocatalytic activity towards H2O2 in the interference-free cathodic region. In addition, cholesterol oxidase was immobilized on the PB/CPANI-modified paper-based electrode for selective detection of cholesterol. Under optimum conditions, a linear range of 0.6-6.0 mM with a very low detection limit of 0.52 mM for cholesterol and a good sensitivity of 411.7 μA mM-1 cm-2 were obtained which indicated that the method presented is outstandingly appropriate to determine cholesterol in bovine serum albumin. This work might be an alternative, interference-free, and cost-effective approach for biomonitoring of cholesterol both in methodological studies and in clinical laboratories. © 2016 The Royal Society of Chemistry.
Subject(s)
Body fluids
Chemical detection
Cost effectiveness
Electrodes
Nanocomposites
Paper
Polyaniline
Sonochemistry
Bovine serum albumins
Cholesterol detection
Cost-effective approach
Cyclic voltammograms
Electrocatalytic activity
Electrochemical studies
Hybrid nanocomposites
Methodological studies
Cholesterol
Composites
Prints
Sterols
Chemical detection
Cost effectiveness
Electrodes
Nanocomposites
Paper
Polyaniline
Sonochemistry
Bovine serum albumins
Cholesterol detection
Cost-effective approach
Cyclic voltammograms
Electrocatalytic activity
Electrochemical studies
Hybrid nanocomposites
Methodological studies
Cholesterol
Composites
Prints
Sterols