Publication:
Uropathogens and empiric antibiotics for the treatment of urinary tract infections in spinal cord injured patients at Rehabilitation Center, Thai Red Cross Society during 2001 to 2005

0
0

Issued Date

2007

Resource Type

Article

File Type

application/pdf

ISSN

1252208

Other identifier(s)

2-s2.0-37149054943

Rights Holder(s)

Scopus

Bibliographic Citation

Journal of the Medical Association of Thailand. Vol 90, No.11 (2007), p.2482-2486

Suggested Citation

Tantisiriwat N., Kittisomprayoonkul W., Sukonthamarn K., Unhasuta C., Suankratay C., Tantisiriwat W., Aksaranugraha S. Uropathogens and empiric antibiotics for the treatment of urinary tract infections in spinal cord injured patients at Rehabilitation Center, Thai Red Cross Society during 2001 to 2005. Journal of the Medical Association of Thailand. Vol 90, No.11 (2007), p.2482-2486. Retrieved from: https://hdl.handle.net/20.500.14740/4309

Title

Uropathogens and empiric antibiotics for the treatment of urinary tract infections in spinal cord injured patients at Rehabilitation Center, Thai Red Cross Society during 2001 to 2005

Author(s)

Tantisiriwat N.
 Kittisomprayoonkul W.
 Sukonthamarn K.
 Unhasuta C.
 Suankratay C.
 Tantisiriwat W.
 Aksaranugraha S.

Abstract

Background: Urinary tract infection (UTI) is common in spinal cord injured patients. The authors investigated the epidemiology of bacteria associated with UTI to select an appropriate antibiotic for empirical treatment of UTI before obtaining a bacterial culture. Objective: To determine the prevalence, as well as the causative bacteria and their susceptibility pattern of urinary tract infection in spinal cord injured patients hospitalized to the Rehabilitation Center, Thai Red Cross Society, Samutprakarn, Thailand from January 2001 to December 2005. Material and Method: A retrospective chart review of 76 spinal cord injured patients. Results: Of all spinal cord injured patients, there were 50 males and 26 females, with the average age of 44.70 years. The average length of hospitalization was 104.5 days. 71.2% of the patients needed intermittent catheterization for bladder drainage, and only 2.7% had suprapubic cystostomy. None of patient had indwelling catheterization. Forty-six patients had 68 episodes of UTI (60.52%). Eighteen patients had recurrent UTI (14 patients had two episodes and four patients had three episodes). E. coli was the most common isolated pathogen (74.36%) followed by K.pneumoniae (12.82%), E. faecalis (5%) and P. mirabilis (5%). Most gramnegative pathogens were susceptible to amikacin and third generation cephalosporins. The susceptibility of these organisms to cotrimoxazole, amoxicillin/clavulanate, and ciprofloxacin were in the range of 34.6-60.0%, 44.0-50.0% and 25.9-50.0%, respectively. Conclusion: Urinary tract infections were commonly observed among spinal cord injured patients in the presented institution. E. coli was the most common isolated pathogen. Surprisingly, most gram-negative pathogens were resistant to cotrimoxazole, amoxicillin/clavulanate, and ciprofloxacin. An antibiotic of choice for UTI in our patients should be aminoglycoside or third generation cephalosporins.

Subject(s)

Amikacin
 Amoxicillin
 Ceftazidime
 Cephalosporin derivative
 Ciprofloxacin
 Clavulanic acid
 Cotrimoxazole
 Adult
 Antibiotic sensitivity
 Article
 Catheterization
 Citrobacter
 Controlled study
 Enterococcus faecalis
 Female
 Hospitalization
 Human
 Klebsiella pneumoniae
 Major clinical study
 Male
 Pathogenesis
 Proteus mirabilis
 Rehabilitation center
 Spinal cord injury
 Urinary tract infection
 Uropathogenic Escherichia coli
 Adult
 Amikacin
 Anti-Bacterial Agents
 Cephalosporins
 Escherichia coli Infections
 Female
 Health Status Indicators
 Humans
 Length of Stay
 Male
 Prevalence
 Red Cross
 Rehabilitation Centers
 Retrospective Studies
 Sickness Impact Profile
 Societies, Medical
 Spinal Cord Injuries
 Thailand
 Urinary Tract Infections

View online Resources

Research Projects

Organizational Units

Journal Issue

URI

https://hdl.handle.net/20.500.14740/4309

Collections

Scopus: Year 1983-2021

Endorsement

Review

Supplemented By

Referenced By