Publication:
Efficacy of fresh lime for smoking cessation

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Issued Date

2012

Resource Type

Article

File Type

application/pdf

ISSN

1252208

Other identifier(s)

2-s2.0-84876888179

Rights Holder(s)

Scopus

Bibliographic Citation

Journal of the Medical Association of Thailand. Vol 95, No.SUPPL.12 (2012), p.S76-S82

Suggested Citation

Rungruanghiranya S., Ekpanyaskul C., Sakulisariyaporn C., Watcharanat P., Akkalakulawas K. Efficacy of fresh lime for smoking cessation. Journal of the Medical Association of Thailand. Vol 95, No.SUPPL.12 (2012), p.S76-S82. Retrieved from: https://hdl.handle.net/20.500.14740/6865

Title

Efficacy of fresh lime for smoking cessation

Author(s)

Rungruanghiranya S.
 Ekpanyaskul C.
 Sakulisariyaporn C.
 Watcharanat P.
 Akkalakulawas K.

Abstract

Objective: To determine the efficacy of fresh lime as a smoking cessation aid compared with nicotine gum. Material and Method: A randomized, controlled trial was conducted between March 2009 and September 2009. Only regular smokers aged 18 or older who were willing to quit were randomized to receive either fresh lime (n = 47) or nicotine gum (n = 53). Smokers were excluded if they were using other smoking cessation aids, allergic to citrus, or had dental problems. Exhaled carbon monoxide (CO)-confirmed continuous abstinence rate (CAR) during week 9-12 was measured as the primary outcomes. To grade the severity of craving, a 100-mm visual analogue scale (VAS) was used. Results: There was no significant difference in CO-confirmed CAR between the fresh lime group and the nicotine gum group during weeks 9-12 (61.7% vs. 66.0%; p = 0.65), although 7-day point prevalence abstinence at week 4 of the fresh lime users was statistically significant lower than those using nicotine gum (38.3% vs. 58.5%; p = 0.04). Cravings did not differ significantly between the groups, although fresh lime users tend to report more cravings intensity. Conclusion: Fresh lime can be used effectively as a smoking cessation aid, although not as good as nicotine gum in reducing cravings.

Subject(s)

Carbon monoxide
 Nicotine gum
 Adult
 Article
 Controlled study
 Drug efficacy
 Drug safety
 Female
 Follow up
 Human
 Lime (fruit)
 Major clinical study
 Male
 Prevalence
 Prospective study
 Randomized controlled trial
 Smoking cessation
 Treatment outcome
 Visual analog scale
 Withdrawal syndrome
 Adult
 Chewing Gum
 Chi-Square Distribution
 Citrus aurantiifolia
 Comorbidity
 Female
 Humans
 Male
 Middle Aged
 Prospective Studies
 Smoking Cessation
 Statistics, Nonparametric
 Tobacco Use Cessation Products
 Treatment Outcome

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URI

https://hdl.handle.net/20.500.14740/6865

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Scopus: Year 1983-2021

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