Publication:
Application of modifier-free gold nanoparticle colorimetric sensing for rapid screening and detection of vitamin B1

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Issued Date

2020

Resource Type

Article

File Type

application/pdf

ISSN

11440546

DOI

10.1039/d0nj01401j

Other identifier(s)

2-s2.0-85086181365

Rights Holder(s)

Scopus

Bibliographic Citation

New Journal of Chemistry. Vol 44, No.22 (2020), p.9223-9229

Suggested Citation

Duenchay P., Kaewjua K., Chailapakul O., Siangproh W. Application of modifier-free gold nanoparticle colorimetric sensing for rapid screening and detection of vitamin B1. New Journal of Chemistry. Vol 44, No.22 (2020), p.9223-9229. doi:10.1039/d0nj01401j Retrieved from: https://hdl.handle.net/20.500.14740/4526

Title

Application of modifier-free gold nanoparticle colorimetric sensing for rapid screening and detection of vitamin B1

Author(s)

Duenchay P.
 Kaewjua K.
 Chailapakul O.
 Siangproh W.

Abstract

In this report, we present a transparency sheet-based colorimetric sensor as an alternative platform for the simple, sensitive and selective determination of vitamin B1 in urine samples by using unmodified gold nanoparticles (AuNPs). Samples presenting different concentrations of vitamin B1 were evaluated. The specific analysis is based on the aggregation of AuNPs by vitamin B1 due to the ability to form strong electrostatic interactions between positively charged vitamin B1 and negatively charged AuNPs. In the presence of vitamin B1, a distinctive color change in the AuNPs from red to blue was visualized by the naked eye within 10 minutes without the requirement for surface modification. For quantitative measurement using image processing, a good linear relationship (R2= 0.9913) between the vitamin B1 concentration and average red intensity was obtained in the range of 40-200 ppb. The limit of detection (LOD) and the limit of quantitation (LOQ) for vitamin B1 were found to be 3.002 ppb (S/B = 3) and 10.006 ppb (S/B = 10), respectively. The characteristics of the developed sensors were investigated for precision, accuracy, and sensitivity, and they were validated by classic methods. Statistical analysis proved that the developed sensors were precise, sensitive and accurate and that they can be used effectively for the analysis of vitamin B1 in urine samples. © The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2020.

Subject(s)

Color
 Colorimetry
 Image processing
 Metal nanoparticles
 Colorimetric sensing
 Colorimetric sensors
 Limit of quantitations
 Linear relationships
 Positively charged
 Quantitative measurement
 Selective determination
 Unmodified gold nanoparticles
 Gold nanoparticles
 Ascorbic acid
 Buffer
 Cyanocobalamin
 Gold nanoparticle
 Nicotinamide
 Pantothenic acid
 Polymer
 Pyridoxine
 Riboflavin
 Thiamine
 Unclassified drug
 Vitamin b7
 Vitamin b9
 Accuracy
 Article
 Calibration
 Colorimetry
 Image processing
 Incubation time
 Limit of quantitation
 Porosity
 Priority journal
 Screening
 Static electricity
 Ultraviolet visible spectrophotometry
 Urinalysis
 Zeta potential

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URI

https://hdl.handle.net/20.500.14740/4526

Collections

Scopus: Year 1983-2021

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