Publication:
Evaluation of the Effects of East Indian Sandalwood Oil and α-Santalol on Humans after Transdermal Absorption

3
0

Issued Date

2004

Resource Type

Article

File Type

application/pdf

ISSN

320943

DOI

10.1055/s-2004-815446

Other identifier(s)

2-s2.0-1242297831

Rights Holder(s)

Scopus

Bibliographic Citation

Planta Medica. Vol 70, No.1 (2004), p.3-7

Suggested Citation

Hongratanaworakit T., Heuberger E., Buchbauer G. Evaluation of the Effects of East Indian Sandalwood Oil and α-Santalol on Humans after Transdermal Absorption. Planta Medica. Vol 70, No.1 (2004), p.3-7. doi:10.1055/s-2004-815446 Retrieved from: https://hdl.handle.net/20.500.14740/6466

Title

Evaluation of the Effects of East Indian Sandalwood Oil and α-Santalol on Humans after Transdermal Absorption

Author(s)

Hongratanaworakit T.
 Heuberger E.
 Buchbauer G.

Abstract

The aim of the study was to investigate the effects of East Indian sandalwood oil (Santalum album, Santalaceae) and α-santalol on physiological parameters as well as on mental and emotional conditions in healthy human subjects after transdermal absorption. In order to exclude any olfactory stimulation, the inhalation of the fragrances was prevented by breathing masks. Eight physiological parameters, i.e., blood oxygen saturation, blood pressure, breathing rate, eye-blink rate, pulse rate, skin conductance, skin temperature, and surface electromyogram were recorded. Subjective mental and emotional condition was assessed by means of rating scales. While α-santalol caused significant physiological changes which are interpreted in terms of a relaxing/sedative effect, sandalwood oil provoked physiological deactivation but behavioral activation. These findings are likely to represent an uncoupling of physiological and behavioral arousal processes by sandalwood oil.

Subject(s)

Fragrance
 Plant medicinal product
 Santalol
 Santalum album extract
 Unclassified drug
 Adult
 Article
 Behavior
 Blood oxygen tension
 Blood pressure monitoring
 Breathing apparatus
 Controlled study
 Drug absorption
 Drug effect
 Drug identification
 Electromyography
 Emotion
 Eyelid reflex
 Human
 Human experiment
 Inhalation
 Mask
 Medicinal plant
 Mental health
 Normal human
 Olfactory system
 Physiology
 Pulse rate
 Santalaceae
 Santalum album
 Sedation
 Skin conductance
 Skin temperature
 Stimulation
 Administration, Cutaneous
 Adult
 Blood Pressure
 Drugs, Chinese Herbal
 Electromyography
 Female
 Humans
 Male
 Pain Measurement
 Phytotherapy
 Plant Oils
 Pulse
 Respiration
 Santalum
 Sesquiterpenes
 Skin Absorption
 Skin Temperature
 Santalaceae
 Santalum
 Santalum album

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URI

https://hdl.handle.net/20.500.14740/6466

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Scopus: Year 1983-2021

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