Publication: Gold nanorod-optical fiber for sensing biomolecular interaction
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Issued Date
2020
Resource Type
File Type
application/pdf
ISSN
10139826
Other identifier(s)
2-s2.0-85089317099
Rights Holder(s)
Scopus
Bibliographic Citation
Key Engineering Materials. Vol 853 KEM, (2020), p.81-86
Suggested Citation
Chueaiarrom C., Loedsapchinda N., Puttharugsa C., Pipatpanukul C., Srikhirin T., Houngkamhang N. Gold nanorod-optical fiber for sensing biomolecular interaction. Key Engineering Materials. Vol 853 KEM, (2020), p.81-86. doi:10.4028/www.scientific.net/KEM.853.81 Retrieved from: https://hdl.handle.net/20.500.14740/4827
Abstract
The optical fiber deposits with gold nanorods was successfully accomplished as a biosensor device which sensing to the refractive index change on the surrounding surface. The principle is based on the localized surface plasmon resonance (LSPR) occurs on the metal surface of gold nanorods (AuNRs). The gold nanorods were coated on the glass core fiber surface through the covalent bond. The uncladded area fiber optic was incubated in 5% of (3-Mercaptopropyl) trimethoxysilane (MPTMS) in ethanol for overnight to alter the thiol group on the surface. The gold nanorods with aspect ratio ⁓2.035 was deposited on thiol surface by incubation the optical fiber in gold nanorod solution for 6 hr. The sensor provides the sensitivity of 4.94×104 a.u./RIU. Moreover, antibody for blood grouping was immobilized on the AuNRs-optical fiber to detect the red blood cells. The AuNRs-optical fiber can detect A antigen on the immobilized anti-A surface with Δ%T of 0.98 and can detect B-antigen on the immobilized anti-B surface with Δ%T of 1.78. This work possesses possibility of a simple AuNRs-optical fiber to detect the biomolecular interaction. The authors would like to thank Thailand Center of Excellence in Physics for financial support. © 2020 Trans Tech Publications Ltd, Switzerland.
Subject(s)
Antigens
Aspect ratio
Blood
Gold coatings
Gold deposits
Nanorods
Optical fibers
Plasmons
Refractive index
Surface plasmon resonance
Biomolecular interactions
Financial support
Gold nanorods (AuNRs)
Localized surface plasmon resonance
Metal surfaces
Red blood cell
Refractive index changes
Trimethoxysilane
Gold Nanorods
Aspect ratio
Blood
Gold coatings
Gold deposits
Nanorods
Optical fibers
Plasmons
Refractive index
Surface plasmon resonance
Biomolecular interactions
Financial support
Gold nanorods (AuNRs)
Localized surface plasmon resonance
Metal surfaces
Red blood cell
Refractive index changes
Trimethoxysilane
Gold Nanorods