Publication: The Anthelmintic Effects of Medicinal Plant Extracts Against Paramphistome Parasites, Carmyerius spatiosus
0
0
Issued Date
2019
Resource Type
File Type
application/pdf
ISSN
12302821
Other identifier(s)
2-s2.0-85074017036
Rights Holder(s)
Scopus
Bibliographic Citation
Acta Parasitologica. Vol 64, No.3 (2019), p.566-574
Suggested Citation
Minsakorn S., Nuplod K., Puttarak P., Chawengkirttikul R., Panyarachun B., Ngamniyom A., Charoenkul T., Jaisa-Aad M., Panyarachun P., Anuracpreeda P. The Anthelmintic Effects of Medicinal Plant Extracts Against Paramphistome Parasites, Carmyerius spatiosus. Acta Parasitologica. Vol 64, No.3 (2019), p.566-574. doi:10.2478/s11686-019-00072-6 Retrieved from: https://hdl.handle.net/20.500.14740/5177
Abstract
Introduction: Paramphistomosis is a disease caused by the rumen flukes which cause an acute gastroenteritis and anemia with high mortality particularly in young ruminants. Materials and methods: In this study, we have investigated the anthelmintic effect of medicinal plant extracts from leaves and heartwoods of Cassia siamea L., roots of Plumbago zeylanica L. and Plumbago indica L., and leaves of Terminalia catappa L. against Carmyerius spatiosus. Results: The highest anthelminthic effect on the flukes after 24 h of exposure was found in heartwood ethyl acetate extract of C. siamea (LC50 = 374.30; LC90 = 749.03 ppm), root n-butanol extract of P. zeylanica (LC50 = 1005.12; LC90 = 2411.55 ppm), root hexane, ethyl acetate, and n-butanol extract of P. indica (LC50 = 34.38, 211.34, 506.92; LC90 = 64.09, 496.05, 934.86 ppm), and leaf n-butanol and water extract of T. catappa (LC50 = 487.17, 470.28; LC90 = 913.27, 848.23 ppm). When observed by scanning electron microscopy, the tegument showed similar sequence of morphological changes after treatments with all plant extracts, comprising of swelling of ridges and folds, blebbing, rupturing of the blebs, erosion, lesion and disruption of the tegument. Conclusion: This study is the first report on the anthelmintic activity of plant extracts to C. spatiosus; therefore, these plant extracts are highly effective in the elimination of adult rumen flukes. © 2019, Witold Stefański Institute of Parasitology, Polish Academy of Sciences.
Subject(s)
Anthelmintic agent
Plant extract
Animal
Bovine
Cattle disease
Chemistry
Drug effect
Female
Growth, development and aging
Human
Male
Medicinal plant
Parasitology
Plant root
Trematode
Trematodiasis
Veterinary medicine
Animals
Anthelmintics
Cattle
Cattle Diseases
Female
Humans
Male
Plant Extracts
Plant Roots
Plants, Medicinal
Trematoda
Trematode Infections
Plant extract
Animal
Bovine
Cattle disease
Chemistry
Drug effect
Female
Growth, development and aging
Human
Male
Medicinal plant
Parasitology
Plant root
Trematode
Trematodiasis
Veterinary medicine
Animals
Anthelmintics
Cattle
Cattle Diseases
Female
Humans
Male
Plant Extracts
Plant Roots
Plants, Medicinal
Trematoda
Trematode Infections