Publication:
Outcomes and quality of life after platelet-rich plasma therapy in patients with recalcitrant hindfoot and ankle diseases: A preliminary report of 12 patients

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Issued Date

2013

Resource Type

Article

File Type

application/pdf

ISSN

10672516

DOI

10.1053/j.jfas.2013.04.005

Other identifier(s)

2-s2.0-84879461832

Rights Holder(s)

มหาวิทยาลัยศรีนครินทรวิโรฒ

Bibliographic Citation

Journal of Foot and Ankle Surgery. Vol 52, No.4 (2013), p.475-480

Suggested Citation

Angthong C., Khadsongkram A., Angthong W. Outcomes and quality of life after platelet-rich plasma therapy in patients with recalcitrant hindfoot and ankle diseases: A preliminary report of 12 patients. Journal of Foot and Ankle Surgery. Vol 52, No.4 (2013), p.475-480. doi:10.1053/j.jfas.2013.04.005 Retrieved from: https://hdl.handle.net/20.500.14740/6627

Title

Outcomes and quality of life after platelet-rich plasma therapy in patients with recalcitrant hindfoot and ankle diseases: A preliminary report of 12 patients

Author(s)

Angthong C.
 Khadsongkram A.
 Angthong W.

Abstract

The present study aimed to determine the outcomes and quality of life after platelet-rich plasma therapy in patients with chronic recalcitrant diseases of the hindfoot and ankle and to identify the crucial clinical variables. The records of 12 adult patients with diseases of the hindfoot and ankle were included in the present study. These patients had been treated with platelet-rich plasma from September 2010 to April 2011 after 3 to 6months or more of conservative treatment had been unsuccessful. They had attended the follow-up visits, were consecutively enrolled, and retrospectively studied. A total of 3 mL of autologous platelet-rich plasma was injected under fluoroscopic or ultrasound guidance into the affected areas. All patients had been evaluated using visual analog scale foot and ankle scoring before treatment and at set intervals after treatment. According to their scores at the final follow-up visit (mean 16 months), the patients were allocated to the satisfactory (score ≥ 80; n = 8) and unsatisfactory (score < 80; n = 4) groups. The health-related quality of life was assessed using the Medical Outcomes Study short-form, 36-item survey at the final follow-up visit, because the study was retrospective, and the information was not available before treatment. The mean visual analog score at the final follow-up visit (79.71 ± 17.81) was significantly greater than the mean pretreatment score (57.89 ± 20.77; p = .002). Four patients (33%) had unsatisfactory results. The mean short-form, 36-item score for the satisfactory group (85.23 ± 11.30) was significantly greater than that (57.33 ± 12.91) of the unsatisfactory group (p=003). No definitive factors influencing the outcome of this treatment were found. The substantial number of patients with an unsatisfactory outcome indicates that platelet-rich plasma injection might be an option but might not be a mainstay of nonoperative treatment of problematic conditions of the hindfoot and ankle. The actual benefit of this treatment, including the factors influencing its outcome, are still inconclusive. © 2013 American College of Foot and Ankle Surgeons.

Subject(s)

Achilles tendinitis
 Adult
 Aged
 Ankle osteoarthritis
 Article
 Bursitis
 Clinical article
 Clinical effectiveness
 Conservative treatment
 Controlled study
 Female
 Foot disease
 Human
 Male
 Nuclear magnetic resonance imaging
 Osteoarthritis
 Plasmapheresis
 Quality of life
 Recalcitrant disease of the hindfoot and ankle
 Retrocalcaneal bursitis
 Retrospective study
 Scoring system
 Short Form 36
 Synovitis
 Thrombocyte rich plasma
 Treatment duration
 Treatment response
 Visual analog scale
 Adolescent
 Adult
 Aged
 Ankle Joint
 Female
 Follow-Up Studies
 Humans
 Joint Diseases
 Male
 Middle Aged
 Patient Satisfaction
 Platelet-Rich Plasma
 Quality of Life
 Retrospective Studies
 Treatment Outcome
 Young Adult

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URI

https://hdl.handle.net/20.500.14740/6627

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Scopus: Year 1983-2021

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