Publication: Assessment of side effects after serial intralesional steroid injections for idiopathic subglottic stenosis
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Issued Date
2021
Resource Type
File Type
application/pdf
ISSN
9374477
Other identifier(s)
2-s2.0-85091151995
Rights
Srinakharinwirot University
Rights Holder(s)
Scopus
Bibliographic Citation
European Archives of Oto-Rhino-Laryngology. Vol 278, No.2 (2021), p.445-450
Suggested Citation
Celebi O.O., Song S.A., Santeerapharp A., Choksawad K., Franco R.A., Jr. Assessment of side effects after serial intralesional steroid injections for idiopathic subglottic stenosis. European Archives of Oto-Rhino-Laryngology. Vol 278, No.2 (2021), p.445-450. doi:10.1007/s00405-020-06371-3 Retrieved from: https://hdl.handle.net/20.500.14740/4381
Abstract
Purpose: To assess the incidence and severity of 12 systemic side effects of serial intralesional steroid injections (SILSI) in patients with idiopathic subglottic stenosis (iSGS). Methods: This retrospective study included patients with iSGS who underwent SILSI with Triamcinolone 40 mg/dL. After SILSI, the patients were asked to answer 12 questions regarding frequently encountered systemic side effects of steroids. Each answer was rated as mild, moderate, or severe. Descriptive statistics were used to analyze and present the findings. Results: The study included 49 patients (42 female and 7 male) with a mean age of 59.1 years (range 21–83 years). Post-SILSI treatment, 27 (55%) reported experiencing side effects while 22 (45%) patients reported no side effects. The most frequent side effect reported in women of reproductive age (n: 8) was menstrual irregularities (3/8, 37%). Other frequently reported side effects were feeling joyful and sleeping difficulties, each reported by 30% of the patients. All side effects resolved after the completion of SILSI. Conclusions: SILSI can be administered with minimal tolerable side effects. Clinicians should make their patients aware of the most frequent side effects. Special attention should be given to women of reproductive age to inform them of the possibility of menstrual irregularities during SILSI. © 2020, Springer-Verlag GmbH Germany, part of Springer Nature.
Subject(s)
Triamcinolone
Adult
Aged
Article
Blood pressure regulation
Clinical article
Controlled study
Depression
Disease severity
Drug tolerability
Fatigue
Female
Human
Idiopathic disease
Idiopathic subglottic stenosis
Idiopathic subglottic stenosis
Incidence
Increased appetite
Loss of appetite
Male
Memory disorder
Menstrual irregularity
Mood change
Priority journal
Retrospective study
Side effect
Sleep disorder
Stomach irritation
Subglottic stenosis
Systemic disease
Adult
Aged
Article
Blood pressure regulation
Clinical article
Controlled study
Depression
Disease severity
Drug tolerability
Fatigue
Female
Human
Idiopathic disease
Idiopathic subglottic stenosis
Idiopathic subglottic stenosis
Incidence
Increased appetite
Loss of appetite
Male
Memory disorder
Menstrual irregularity
Mood change
Priority journal
Retrospective study
Side effect
Sleep disorder
Stomach irritation
Subglottic stenosis
Systemic disease