Publication:
The 2-year outcomes comparison between ischemic stroke patients with intracranial arterial stenosis without significant extracranial carotid stenosis and patients with extracranial carotid stenosis

1
0

Issued Date

2015

Resource Type

Article

File Type

application/pdf

ISSN

1252208

Other identifier(s)

2-s2.0-84957707290

Rights Holder(s)

Scopus

Bibliographic Citation

Journal of the Medical Association of Thailand. Vol 98, (2015), p.S98-S105

Suggested Citation

Methawasin K., Suwanwela N.C., Phanthumchinda K. The 2-year outcomes comparison between ischemic stroke patients with intracranial arterial stenosis without significant extracranial carotid stenosis and patients with extracranial carotid stenosis. Journal of the Medical Association of Thailand. Vol 98, (2015), p.S98-S105. Retrieved from: https://hdl.handle.net/20.500.14740/6081

Title

The 2-year outcomes comparison between ischemic stroke patients with intracranial arterial stenosis without significant extracranial carotid stenosis and patients with extracranial carotid stenosis

Author(s)

Methawasin K.
 Suwanwela N.C.
 Phanthumchinda K.

Abstract

Objective: The risk of recurrent ischemic stroke and acute coronary syndrome increased in the large artery atherosclerotic subtype. The purpose of this study was to compare 2-year outcomes between the ischemic stroke patients with intracranial arterial stenosis without significant extracranial carotid stenosis and the patients with extracranial carotid stenosis. Material and Method: This study prospectively compared 123 ischemic stroke patients: 71 patients with intracranial arterial stenosis without significant extracranial carotid stenosis and 52 patients with extracranial carotid stenosis. Neurologic and radiologic investigations were performed at the beginning of the study. All of them were treated as regular outpatients of the neurology unit with a mean follow-up of 24 months. Recurrent stroke, myocardial infarction, and death were recorded. Results: Fifteen patients of the extracranial carotid stenosis group and eighteen patients of the intracranial arterial stenosis without significant extracranial carotid stenosis group developed recurrent stroke during follow-up (p = 0.40). Acute coronary syndrome occurred in eight patients of the extracranial carotid stenosis group and only one of the intracranial arterial stenosis without significant extracranial carotid stenosis group (p = 0.004). Causes of death were end stage cancers, stroke and related conditions, and acute coronary syndrome. The multivariate analysis showed that symptomatic extracranial carotid stenosis is an important risk factor of the acute coronary syndrome (p = 0.03, OR = 10.81, 95% CI 1.23-94.77). Conclusion: There was no significant difference of recurrent ischemic stroke and recurrent stroke between patients with intracranial arterial stenosis without extracranial carotid stenosis and patients with extracranial carotid stenosis. On the other hand, patients with extracranial carotid stenosis had more incidences of acute coronary syndrome significantly than patients with intracranial arterial stenosis. © 2015, Medical Association of Thailand. All rights reserved.

Subject(s)

Acute coronary syndrome
 Adult
 Aged
 Artery occlusion
 Article
 Brain hemorrhage
 Brain infarction
 Carotid artery obstruction
 Computer assisted tomography
 Controlled study
 Death
 Doppler echography
 Female
 Heart muscle ischemia
 Human
 Major clinical study
 Male
 Nuclear magnetic resonance imaging
 Outcome assessment
 Prospective study
 Questionnaire
 Risk factor
 Transient ischemic attack
 Acute coronary syndrome
 Brain atherosclerosis
 Carotid artery obstruction
 Complication
 Middle aged
 Pathology
 Pathophysiology
 Stenosis, occlusion and obstruction
 Stroke
 Very elderly
 Acute Coronary Syndrome
 Aged
 Aged, 80 and over
 Carotid Stenosis
 Constriction, Pathologic
 Female
 Humans
 Intracranial Arteriosclerosis
 Male
 Middle Aged
 Prospective Studies
 Risk Factors
 Stroke

View online Resources

Research Projects

Organizational Units

Journal Issue

URI

https://hdl.handle.net/20.500.14740/6081

Collections

Scopus: Year 1983-2021

Endorsement

Review

Supplemented By

Referenced By