Publication: Perioperative Risk Factors for Postoperative Delirium in Non-dementia Older Patients after Non-cardiac Surgery and Anesthesia: A Prospective Study
1
0
Issued Date
2025-03-01
Resource Type
ISSN
25084798
eISSN
25084909
Scopus ID
2-s2.0-105001812977
Journal Title
Annals of Geriatric Medicine and Research
Volume
29
Issue
1
Start Page
45
End Page
52
Rights Holder(s)
SCOPUS
Bibliographic Citation
Annals of Geriatric Medicine and Research Vol.29 No.1 (2025) , 45-52
Suggested Citation
Wattanaboot N., Kuawatcharawong W., Permsakmesub P. Perioperative Risk Factors for Postoperative Delirium in Non-dementia Older Patients after Non-cardiac Surgery and Anesthesia: A Prospective Study. Annals of Geriatric Medicine and Research Vol.29 No.1 (2025) , 45-52. 52. doi:10.4235/agmr.24.0129 Retrieved from: https://hdl.handle.net/20.500.14740/20872
Author(s)
Author's Affiliation
Corresponding Author(s)
Other Contributor(s)
Abstract
Background: To investigate the incidence and perioperative risk factors for postoperative delirium (POD) in non-dementia older patients who underwent anesthesia for non-cardiac surgery. Methods: This prospective cohort study was conducted on 195 non-dementia older patients, aged 60 years or older, who were hospitalized after non-cardiac surgery and anesthesia. The Confusion Assessment Method for the Intensive Care Unit was used to evaluate the occurrence of POD. Incidence of POD was reported. We conducted univariate and multivariate logistic regression to identify the risk factors associated with POD. Results: A total of 195 patients were en-rolled; 172 completed the study. POD occurred in seven patients within three days after anesthe-sia, which is a 4.1% incidence of POD. Multivariate logistic analysis showed arrhythmia, coagulop-athy, urinary comorbidity, minimum intraoperative heart rate, and minimum post-anesthesia care unit (PACU) pain score as independent risk factors for POD. A minimum PACU pain score >1 is the optimum cutoff pain score for developing POD, with a sensitivity of 85.7% and a specificity of 69.1%. The postoperative complication rate and in-hospital mortality were significantly higher for patients with POD compared to those without POD. Conclusion: The incidence of POD in the study population is 4.1%. Arrhythmia, coagulopathy, urinary comorbidity, minimum intraoperative heart rate, and minimum PACU pain score were independent risk factors for POD. The minimum PACU pain score is the strongest independent risk factor of POD. POD is associated with increased postoperative complications and in-hospital mortality rates in non-dementia older patients.