Publication: Expert panel consensus recommendations on the utilization of nebulized budesonide for managing asthma and COPD in both stable and exacerbation stages in Thailand
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Issued Date
2024-01-01
Resource Type
ISSN
02770903
eISSN
15324303
Scopus ID
2-s2.0-85189966324
Pubmed ID
38527278
Journal Title
Journal of Asthma
Volume
61
Issue
10
Start Page
1136
End Page
1151
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Asthma Vol.61 No.10 (2024) , 1136-1151
Suggested Citation
Wongsurakiat P., Rattanawongpaibul A., Limsukon A., Chiewchalermsri C., Wiwatcharagoses K., Kornthatchapong K., Saiphoklang N., Sanguanwit P., Domthong P., Kawamatawong T., Sewatanon T., Reechaipichitkul W., Maneechotesuwan K. Expert panel consensus recommendations on the utilization of nebulized budesonide for managing asthma and COPD in both stable and exacerbation stages in Thailand. Journal of Asthma Vol.61 No.10 (2024) , 1136-1151. 1151. doi:10.1080/02770903.2024.2334897 Retrieved from: https://hdl.handle.net/20.500.14740/20419
Author's Affiliation
Ramathibodi Hospital
Siriraj Hospital
Faculty of Medicine, Chiang Mai University
Thammasat University Hospital
Rangsit University
Srinagarind Hospital
Faculty of Medicine, Thammasat University
Maharaj Nakhon Ratchasima Hospital
Khon Kaen Regional Hospital
Srinakharinwirot University
Thai Asthma Council (TAC)
Udonthani Hospital
Siriraj Hospital
Faculty of Medicine, Chiang Mai University
Thammasat University Hospital
Rangsit University
Srinagarind Hospital
Faculty of Medicine, Thammasat University
Maharaj Nakhon Ratchasima Hospital
Khon Kaen Regional Hospital
Srinakharinwirot University
Thai Asthma Council (TAC)
Udonthani Hospital
Corresponding Author(s)
Other Contributor(s)
Abstract
Objective: This study investigated the utilization of nebulized budesonide for acute asthma and COPD exacerbations as well as for maintenance therapy in adults. Data Sources: We conducted a search on PubMed for nebulized budesonide treatment. Selected Studies: Selecting all English-language papers that utilize Mesh phrases "asthma," "COPD," "budesonide," "nebulized," "adult," "exacerbation," and "maintenance" without temporal restrictions, and narrowing down to clinical research such as RCTs, observational studies, and real-world studies. Results: Analysis of 25 studies was conducted to assess the effectiveness of nebulized budesonide in asthma (n = 10) and COPD (n = 15). The panel in Thailand recommended incorporating nebulized budesonide as an additional or alternative treatment option to the standard of care and systemic corticosteroids (SCS) based on the findings. Conclusion: Nebulized budesonide is effective and well-tolerated in treating asthma and COPD, with less systemic adverse effects compared to systemic corticosteroids. High-dose nebulized budesonide can enhance clinical outcomes for severe and mild exacerbations with slow systemic corticosteroid response. Nebulized budesonide can substitute systemic corticosteroids in some situations.