Publication:
Bilateral acute onset myopia and angle closure glaucoma after oral topiramate: A case report

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Issued Date

2008

Resource Type

Article

File Type

application/pdf

ISSN

1252208

Other identifier(s)

2-s2.0-58949090429

Rights Holder(s)

Scopus

Bibliographic Citation

Journal of the Medical Association of Thailand. Vol 91, No.12 (2008), p.1904-1908

Suggested Citation

Boonyaleephan S. Bilateral acute onset myopia and angle closure glaucoma after oral topiramate: A case report. Journal of the Medical Association of Thailand. Vol 91, No.12 (2008), p.1904-1908. Retrieved from: https://hdl.handle.net/20.500.14740/3760

Title

Bilateral acute onset myopia and angle closure glaucoma after oral topiramate: A case report

Author(s)

Boonyaleephan S.

Abstract

Objective: Describe bilateral acute onset myopia and angle-closure glaucoma as ocular adverse effects of topiramate. Case Report: A 23 year-old woman developed bilateral severe blurred vision seven days after initiating therapy with topiramate. Her visual acuity was counting fingers in both eyes. Intraocular pressures were 33 mmHg and 32 mmHg in the right and left eyes, respectively, with conjunctival chemosis, corneal edema, shallow anterior chambers, and closed angles. Her refraction was -7.50 diopters in both eyes. The symptoms and clinical findings resolved completely upon discontinuation of topiramate and administration of antiglaucoma drugs. Conclusion: Topiramate use can result in acute bilateral angle-closure glaucoma and myopia, which are usually reversible upon cessation of the drug. Visual outcome is usually good and the episode resolves within a few weeks. Thus, it is important for clinicians to recognize these conditions and educate patients about these serious adverse effects when prescribing topiramate.

Subject(s)

Acetazolamide
 Amitriptyline
 Antiglaucoma agent
 Glycerol
 Mefenamic acid
 Prednisolone acetate
 Propranolol derivative
 Timolol maleate
 Topiramate
 Acetazolamide
 Anticonvulsive agent
 Antihypertensive agent
 Cryoprotective agent
 Drug derivative
 Fructose
 Glycerol
 Timolol
 Topiramate
 Adult
 Anterior eye chamber
 Article
 Biomicroscopy
 Blurred vision
 Case report
 Chemosis
 Closed angle glaucoma
 Cornea edema
 Drug withdrawal
 Eye examination
 Eye pain
 Eye refraction
 Female
 Human
 Intraocular pressure
 Migraine
 Myopia
 Photography
 Side effect
 Visual acuity
 Acute disease
 Chemically induced disorder
 Closed angle glaucoma
 Drug effect
 Myopia
 Risk factor
 Acetazolamide
 Acute Disease
 Adult
 Anticonvulsants
 Antihypertensive Agents
 Cryoprotective Agents
 Female
 Fructose
 Glaucoma, Angle-Closure
 Glycerol
 Humans
 Intraocular Pressure
 Myopia
 Risk Factors
 Timolol

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URI

https://hdl.handle.net/20.500.14740/3760

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Scopus: Year 1983-2021

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