Publication:
Iridoid Glucosides from the Flowers of Barleria lupulina

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Issued Date

2003

Resource Type

Article

File Type

application/pdf

ISSN

320943

DOI

10.1055/s-2003-43223

Other identifier(s)

2-s2.0-0242320483

Rights Holder(s)

มหาวิทยาลัยศรีนครินทรวิโรฒ

Bibliographic Citation

Planta Medica. Vol 69, No.9 (2003), p.877-879

Suggested Citation

Suksamrarn S., Wongkrajang K., Kirtikara K., Suksamrarn A. Iridoid Glucosides from the Flowers of Barleria lupulina. Planta Medica. Vol 69, No.9 (2003), p.877-879. doi:10.1055/s-2003-43223 Retrieved from: https://hdl.handle.net/20.500.14740/6565

Title

Iridoid Glucosides from the Flowers of Barleria lupulina

Author(s)

Suksamrarn S.
 Wongkrajang K.
 Kirtikara K.
 Suksamrarn A.

Abstract

A new iridoid diglucoside, lupulinoside, and eight known iridoid glucosides, acetylbarlerin, ipolamiidoside (3), 6-O-acetylshanzhiside methyl ester, barlerin, shanzhiside methyl ester, mussaenosidic acid, 8-O-acetylshanzhiside, and shanzhiside have been isolated from the flowers of Barleria lupulina. The structure of the new compound was established as 8-O-acetyl-2′-O-(β-glucopyranosyl)mussaenoside by spectroscopic, especially 2D NMR, techniques. When tested for anti-herpes simplex type 1 activity, only compound 3 exhibited antiviral properties. None of the compounds showed cytotoxic effects to the vero cells and none of them inhibited cyclooxygenase-2 enzyme.

Subject(s)

6 o acetylshanzhiside methyl ester
 8 o acetylshanzhiside
 Acetylbarlerin
 Barlerin
 Cyclooxygenase 2
 Glucoside
 Ipolamiidoside
 Iridoid
 Mussaenosidic acid
 Natural product
 Plant extract
 Shanzhiside
 Shanzhiside methyl ester
 Unclassified drug
 Antiviral activity
 Article
 Barleria lupulina
 Drug isolation
 Flower
 Herpes simplex virus 1
 Medicinal plant
 Nonhuman
 Phytochemistry
 Proton nuclear magnetic resonance
 Structure activity relation
 Acanthaceae
 Antiviral Agents
 Flowers
 Herpesvirus 1, Human
 Humans
 Iridoids
 Microbial Sensitivity Tests
 Phytotherapy
 Plant Extracts
 Barleria
 Barleria lupulina
 DNA viruses
 Human herpesvirus 1
 Simplexvirus

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URI

https://hdl.handle.net/20.500.14740/6565

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Scopus: Year 1983-2021

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