Publication:
Accuracy of transcutaneous bilirubinometry compare to total serum bilirubin measurement

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Issued Date

2010

Resource Type

Article

File Type

application/pdf

ISSN

1252208

Other identifier(s)

2-s2.0-79952257422

Rights Holder(s)

Scopus

Bibliographic Citation

Journal of the Medical Association of Thailand. Vol 93, No.SUPPL 2 (2010), p.S81-S86

Suggested Citation

Panburana J., Boonkasidach S., Rearkyai S. Accuracy of transcutaneous bilirubinometry compare to total serum bilirubin measurement. Journal of the Medical Association of Thailand. Vol 93, No.SUPPL 2 (2010), p.S81-S86. Retrieved from: https://hdl.handle.net/20.500.14740/7489

Title

Accuracy of transcutaneous bilirubinometry compare to total serum bilirubin measurement

Author(s)

Panburana J.
 Boonkasidach S.
 Rearkyai S.

Abstract

Background: Neonatal hyperbilirubinemia leads to bilirubin neurotoxicity. Noninvasive transcutaneous bilirubin (TcB) levels can be used as a screening tool for total serum bilirubin (TSB) levels. Objective: To evaluate the correlation of TcB for TSB levels before, during and after phototherapy and find the most reliable cutoff values of TcB levels with the highest sensitivity and specificity for TSB levels. Design: Diagnostic study. Material and Method: In this research, forehead TcB measurement was measured by the transcutaneous bilirubinometer (Minolta Airshilds Jaundice Meter, JM 103). The 224 paired TcB-TSB specimens from 74 term and nearterm newborns were study from September 2007 to October 2008. The mean postnatal age at the time of measurement was 57.85 + 22.15 hours. The mean gestational age was 38 + 1.29 weeks and mean body weight was 2,864.65 + 262 g. Results: The TcB and TSB values had linear correlation with significant correlation coefficient (r 0.81, p < 0.001). The correlation equation was TSB = 0.88 + 0.89 x TcB (r2 = 0.65). TcB levels tended be higher than TSB with mean difference of 0.44 mg/dL (95% CI: 0.7433-0.1323 mg/dL) and SD:1.64. TSB confirmation was recommended when TcB cutoff values greater than 9, 12, 13, 15 mg/dL at 24 (TSB:8 mg/dL), 36 (TSB:10 mg/ dL), 48 (TSB:12mg/dL) and 72 (TSB:15mg/dL) hours' postnatalage, respectively. Conclusion: The TcB levels can accurately predict TSB with the different cutoff points at various postnatal ages before phototherapy.

Subject(s)

Bilirubin
 Article
 Blood
 Blood analysis
 Comparative study
 Evaluation
 Female
 Gestational age
 Human
 Instrumentation
 Male
 Metabolism
 Methodology
 Newborn
 Newborn jaundice
 Newborn screening
 Phototherapy
 Pregnancy
 Receiver operating characteristic
 Reproducibility
 Sensitivity and specificity
 Skin
 Spectrophotometry
 University hospital
 Bilirubin
 Blood Chemical Analysis
 Female
 Gestational Age
 Hospitals, University
 Humans
 Hyperbilirubinemia, Neonatal
 Infant, Newborn
 Male
 Neonatal Screening
 Phototherapy
 Pregnancy
 Reproducibility of Results
 ROC Curve
 Sensitivity and Specificity
 Skin
 Spectrophotometry

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URI

https://hdl.handle.net/20.500.14740/7489

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Scopus: Year 1983-2021

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