Prevalence of cirrhosis registered in Nakhon Nayok, Thailand

Abstract

Objective: To determine population-based prevalence rates of cirrhosis in Nakhon Nayok Province and patterns of the prevalence by sex, age groups and disease type. Material and Method: A retrospective descriptive study of medical record database was performed in all hospitals in the province of Nakhon Nayok during the year 2007. ICD-10 was used to identify patients with cirrhosis. Patient information was collected, including name, sex, address and age and data of population of Nakhon Nayok Province stratified by 5 year-age groups, sex and district of the province were obtained. Crude and standardised prevalence rates were calculated using WHO (2000) standard population. Results: There were 199 cirrhosis patients comprising 111 males (55.8%) and 88 females (44.2%) with average age of 54.7 years (SD, 13.0). Crude prevalence rate per 100,000 was 86.3 (95% CI: 74.3-98.3) and age standardized prevalence rate was 75.3 (95% CI: 64.8-85.8). Prevalence of alcoholic cirrhosis was 53.6 (95% CI: 44.8-62.5) and 21.7 (95% CI: 16.0-27.4) for non-alcoholic cirrhosis. Alcoholic cirrhosis in male was found in younger age groups than older age. The prevalence rates vary among four districts. Discussion: In this rural area in the central part of Thailand, the standardized prevalence rates is 75.3 per 100,000 and the prevalence is more common in male than female especially for alcoholic cirrhosis. Prevalence of cirrhosis starts to rise from age of 30 to 60 years. Age distributions of non alcoholic cirrhosis in males and females are similar but in alcoholic cirrhosis the magnitude of prevalence in male is higher than female. Alcoholic cirrhosis is 2.6 folds more prevalent than non-alcoholic cirrhosis.