Publication: Continuous tremor monitoring in Parkinson's disease: A wristwatch-inspired triboelectric sensor approach
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Issued Date
2024-12-20
Resource Type
eISSN
25890042
Scopus ID
2-s2.0-85211145778
Journal Title
iScience
Volume
27
Issue
12
Rights Holder(s)
SCOPUS
Bibliographic Citation
iScience Vol.27 No.12 (2024)
Suggested Citation
Ukasi S., Pongampai S., Panigrahi B.K., Panda S., Hajra S., Kim H.J., Vittayakorn N., Charoonsuk T. Continuous tremor monitoring in Parkinson's disease: A wristwatch-inspired triboelectric sensor approach. iScience Vol.27 No.12 (2024). doi:10.1016/j.isci.2024.111480 Retrieved from: https://hdl.handle.net/20.500.14740/20608
Corresponding Author(s)
Other Contributor(s)
Abstract
Parkinson's disease (PD) prevalence is projected to reach 12 million by 2040. Wearable sensors offer a promising approach for comfortable, continuous tremor monitoring to optimize treatment strategies. Here, we present a wristwatch-like triboelectric sensor (WW-TES) inspired by automatic watches for unobtrusive PD tremor assessment. The WW-TES utilizes a free-standing design with a surface-modified polytetrafluoroethylene (PTFE) film and a stainless-steel rotor within a biocompatible polylactic acid (PLA) package. Electrode distance is optimized to maximize the output signal. We propose and discuss the WW-TES working mechanism. The final design is validated for activities of daily living (ADLs), with varying signal amplitudes corresponding to tremor severity levels (“normal” to “severe”) based on MDS-UPDRS tremor frequency. Wavelet packet transform (WPT) is employed for signal analysis during ADLs. The WW-TES demonstrates the potential for continuous tremor monitoring, offering an accurate screening of severity and comfortable, unobtrusive wearability.