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dc.contributor.authorTrisomboon H.
dc.contributor.authorMalaivijitnond S.
dc.contributor.authorWatanabe G.
dc.contributor.authorTaya K.
dc.date.accessioned2021-04-05T04:32:37Z-
dc.date.available2021-04-05T04:32:37Z-
dc.date.issued2005
dc.identifier.issn1355008X
dc.identifier.other2-s2.0-23844558954
dc.identifier.urihttps://ir.swu.ac.th/jspui/handle/123456789/15100-
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-23844558954&partnerID=40&md5=f3e64118fd049acaf2790128179b757c
dc.description.abstractPueraria mirifica (PM), a Thai herb containing phytoestrogens, may act as estrogen and disturb reproduction. To investigate the effect of PM on the menstrual cycle length and related hormones, nine adult female monkeys (Macaca fascicularis) were separated into three groups. Each group (n = 3) was fed with 10, 100, and 1000 mg/d of PM for three menstrual cycles. The menstrual cycle length increased significantly in mon-keys treated with PM-10 and PM-100 and disappeared completely in monkeys treated with PM-1000. Serum follicle stimulating hormone, luteinizing hormone, estradiol, progesterone, and ir-inhibin were lower during the treatment period in a dose-dependent manner. Changes in menstrual cycle length and the hormonal levels recovered during the post-treatment period only in monkeys treated with PM-10 and PM-100. PM greatly influences menstrual cycles and may suppress ovulation by lowering serum levels of gonadotropins. © 2005 by Humana Press Inc. All rights of any nature whatsoever reserved.
dc.subjectestradiol
dc.subjectfollitropin
dc.subjectgonadotropin
dc.subjectinhibin
dc.subjectluteinizing hormone
dc.subjectphytoestrogen
dc.subjectprogesterone
dc.subjectestradiol
dc.subjectfollitropin
dc.subjectinhibin
dc.subjectluteinizing hormone
dc.subjectphytoestrogen
dc.subjectprogesterone
dc.subjectanimal experiment
dc.subjectarticle
dc.subjectdose response
dc.subjectestradiol blood level
dc.subjectfeeding
dc.subjectfemale
dc.subjectfollitropin blood level
dc.subjectgonadotropin blood level
dc.subjectherb
dc.subjecthormone blood level
dc.subjecthormone determination
dc.subjectluteinizing hormone blood level
dc.subjectMacaca
dc.subjectmenstrual cycle
dc.subjectmonkey
dc.subjectnonhuman
dc.subjectovulation inhibition
dc.subjectpeuraria mirifica
dc.subjectpriority journal
dc.subjectprogesterone blood level
dc.subjectThailand
dc.subjectanimal
dc.subjectblood
dc.subjectdrug effect
dc.subjectmenstrual cycle
dc.subjectPueraria
dc.subjectAnimals
dc.subjectEstradiol
dc.subjectFemale
dc.subjectFollicle Stimulating Hormone
dc.subjectInhibins
dc.subjectLuteinizing Hormone
dc.subjectMacaca fascicularis
dc.subjectMenstrual Cycle
dc.subjectOvulation Inhibition
dc.subjectPhytoestrogens
dc.subjectProgesterone
dc.subjectPueraria
dc.titleOvulation block by Pueraria mirifica: A study of its endocrinological effect in female monkeys
dc.typeArticle
dc.rights.holderScopus
dc.identifier.bibliograpycitationEndocrine. Vol 26, No.1 (2005), p.33-39
Appears in Collections:Scopus 1983-2021

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