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https://ir.swu.ac.th/jspui/handle/123456789/14246| Title: | Uvaridacols E-H, highly oxygenated antiausterity agents from Uvaria dac |
| Authors: | Awale S. Ueda J.-Y. Athikomkulchai S. Dibwe D.F. Abdelhamed S. Yokoyama S. Saiki I. Miyatake R. |
| Keywords: | antineoplastic agent cyclohexene derivative herbaceous agent unclassified drug uvaridacol e uvaridacol f uvaridacol h Annonaceae article cancer cell circular dichroism drug structure human human cell nuclear magnetic resonance pancreas cancer plant stem spectroscopy Uvaria dac |
| Issue Date: | 2012 |
| Abstract: | Chemical investigation of the stems of Uvaria dac yielded four new highly oxygenated cyclohexene derivatives named uvaridacols E-H (1-4). Their structures were established through NMR and circular dichroism spectroscopic analysis. Uvaridacols E (1), F (2), and H (4) displayed weak preferential cytotoxicity against PANC-1 human pancreatic cancer cells under nutrition-deprived conditions in a concentration-dependent manner, without causing toxicity in normal nutrient-rich conditions. © 2012 The American Chemical Society and American Society of Pharmacognosy. |
| URI: | https://ir.swu.ac.th/jspui/handle/123456789/14246 https://www.scopus.com/inward/record.uri?eid=2-s2.0-84870167887&doi=10.1021%2fnp300596c&partnerID=40&md5=04d0061db3c46e10ce297bb99d0386ab |
| ISSN: | 1633864 |
| Appears in Collections: | Scopus 1983-2021 |
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