Please use this identifier to cite or link to this item: http://ir.swu.ac.th/jspui/handle/123456789/13130
Title: An efficacy and safety of nanofractional radiofrequency for the treatment of striae alba
Authors: Pongsrihadulchai N.
Chalermchai T.
Ophaswongse S.
Pongsawat S.
Udompataikul M.
Keywords: collagen
corticosteroid
elastin
hydroquinone
retinoid
abdomen
adult
Article
buttock
clinical article
clinical assessment
epidermis
female
histopathology
human
male
microneedle
nanofractional radiofrequency
prevalence
radiofrequency
safety
skin scar
stria
striae alba
thigh
adverse effects
catheter ablation
middle aged
pathology
patient satisfaction
procedures
single blind procedure
Striae Distensae
treatment outcome
young adult
Abdomen
Adult
Buttocks
Catheter Ablation
Female
Humans
Male
Middle Aged
Patient Satisfaction
Single-Blind Method
Striae Distensae
Thigh
Treatment Outcome
Young Adult
Issue Date: 2017
Abstract: Background: Striae distensae (SD) is a form of dermal scar. A number of treatments have been proposed, but they usually have unsatisfactory result especially in striae alba. Recently, nanofractional RF has been developed. Its mechanism of action is to stimulate dermal remodeling and epidermal re-epithelization. Aim: To evaluate the efficacy and safety of nanofractional RF in the treatment of striae alba. Patients/Methods: This is an experimental, assessor-blinded, before–after study. Thirty-three subjects, with striae alba on their thighs, abdomen, or buttocks (11 subjects each) were enrolled. Treatments with nanofractional RF were undergone for a total of three sessions at 4-week intervals. Clinical outcomes were assessed, by comparing pre- and post-treatment measurement of total lesional surface area (using digital Pictzar™ software), and length and width of lesions. Histopathological evaluation was also performed. Results: At 4 weeks after the last treatment, the total surface area, and the width and the length of striae alba significantly decreased from the baseline (P < 0.001). Postinflammatory hyperpigmentation was reported in six subjects. Regarding histopathology, the average mean number of collagen and elastin bundles was significantly increased (P = 0.005 and 0.012, respectively). Conclusion: Nanofractional RF is highly effective with a good safety profile for the treatment of striae alba. © 2016 Wiley Periodicals, Inc.
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84992382905&doi=10.1111%2fjocd.12292&partnerID=40&md5=78670f8759edb308ba602b2f003d39d7
http://ir.swu.ac.th/jspui/handle/123456789/13130
ISSN: 14732130
Appears in Collections:Scopus 1983-2021

Files in This Item:
There are no files associated with this item.


Items in SWU repository are protected by copyright, with all rights reserved, unless otherwise indicated.