Please use this identifier to cite or link to this item: http://ir.swu.ac.th/jspui/handle/123456789/12977
Title: A low cost and simple lab-on-a-chip for spectrophotometric determination of ethanol
Authors: Somsaeng T.
Pumsa-Ard K.
Jittangprasert P.
Issue Date: 2018
Abstract: A simple lab-on-a-chip system was developed for the rapid determination of ethanol in different sample matrices, including gasohol and various alcoholic beverages. The colorimetric detection of ethanol using a spectrophotometer was based on the reaction between ethanol with 0.12 M ceric ammonium nitrate in acidic medium to produce a red colored product which gave a maximum absorption at 470 nm. A non-lithographic method was used for creating lab-on-a-chip molds to reduce manufacturing cost and preparation steps. The lab-on-a-chip device was fabricated from polydimethylsiloxane which consisted of a simple Y-shaped working channel. Under optimum conditions, a linear calibration graph was obtained in the concentration range of 0.20-20 % (v/v) (r2> 0.999). The limit of detection (3 SD) and limit of quantification (10 SD) were 0.039 and 0.13 % (v/v), respectively. The precision reported in terms of relative standard deviation (RSD) values was less than 1.40 % (n = 15). To demonstrate the lab-on-a-chip’s performance, the determination of ethanol in gasohol and various alcoholic beverages was applied. The results obtained from the developed method compared with a standard gas chromatographic method were well correlated using the paired t-test and linear regression test. The results indicate that the proposed method has shown potential to extend the use of this simple lab-on-a-chip analytical device, due to its simplicity, low cost, lower reagent and sample consumption and high analytical performance. Moreover, the method of fabrication would be an additive manufacturing technique featuring a low equipment cost with no need for clean rooms. © 2018, Walailak University. All rights reserved.
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047803646&partnerID=40&md5=07353c3abcc493a433f31670ec779577
http://ir.swu.ac.th/jspui/handle/123456789/12977
ISSN: 16863933
Appears in Collections:Scopus 1983-2021

Files in This Item:
There are no files associated with this item.


Items in SWU repository are protected by copyright, with all rights reserved, unless otherwise indicated.