Please use this identifier to cite or link to this item: http://ir.swu.ac.th/jspui/handle/123456789/12812
Title: Non-Hodgkin lymphoma in South East Asia: An analysis of the histopathology, clinical features, and survival from Thailand
Authors: Intragumtornchai T.
Bunworasate U.
Wudhikarn K.
Lekhakula A.
Julamanee J.
Chansung K.
Sirijerachai C.
Norasetthada L.
Nawarawong W.
Khuhapinant A.
Siritanaratanakul N.
Numbenjapon T.
Prayongratana K.
Chuncharunee S.
Niparuck P.
Suwanban T.
Kanitsap N.
Wongkhantee S.
Pornvipavee R.
Wong P.
Makruasi N.
Wannakrairot P.
Assanasen T.
Sukpanichnant S.
Boonsakan P.
Kanoksil W.
Ya-in C.
Kayasut K.
Mitranun W.
Warnnissorn N.
Keywords: anaplastic lymphoma kinase
cyclophosphamide
doxorubicin
prednisolone
rituximab
vincristine
adult
aged
anaplastic large cell lymphoma
Article
B cell lymphoma
cancer chemotherapy
cancer survival
China
clinical feature
cohort analysis
comparative study
diffuse large B cell lymphoma
female
follicular lymphoma
follow up
histology
histopathology
human
Human immunodeficiency virus infection
human tissue
Korea
long term survival
lymphoblastoma
major clinical study
male
marginal zone lymphoma
middle aged
NK T cell lymphoma
nonhodgkin lymphoma
overall survival
peripheral T cell lymphoma
prevalence
priority journal
subcutaneous t cell lymphoma
Thailand
adolescent
mortality
nonhodgkin lymphoma
pathophysiology
Southeast Asia
survival analysis
Thailand
very elderly
young adult
Adolescent
Adult
Aged
Aged, 80 and over
Asia, Southeastern
Female
Humans
Lymphoma, Non-Hodgkin
Male
Middle Aged
Survival Analysis
Thailand
Young Adult
Issue Date: 2018
Abstract: Systemic reports on the descriptive epidemiology of non-Hodgkin lymphoma (NHL) from Southeast Asia are scarce. A nationwide multi-institutional registry was conducted to compare the histopathology, clinical features, and survival of Thai adult patients with NHL using large registries, especially those from Far East Asia (FEA). Using a web-based registry system, 13 major medical centers from the 4 geographic regions of Thailand prospectively collected, from 2007 to 2014, the diagnostic pathology, according to the World Health Organization classification, 2008, clinical features and survival of 4056 patients who were newly diagnosed with NHL. The median age of the patients was 56 years (range, 16-99 years). The male-to-female ratio was 1.3:1. From the total of 4056 patients, T/NK-cell lymphoma (TNKCL) accounted for 12.6% of cases, and 5.1% had human immunodeficiency virus–associated lymphoma. The four leading histological subtypes were diffuse large B-cell lymphoma, not otherwise specified (58.1%); follicular lymphoma (5.6%); extranodal mucosa-associated lymphoid tissue lymphoma (5.2%); and peripheral T-cell lymphoma, not otherwise specified (4.0%). With a median follow-up duration of 46.1 months, the median overall survival of B-cell NHL was significantly longer than that of patients with TNKCL (76.5 vs 28.8 months, P =.0001). Compared to FEA, the Thai registry had an approximately one-half lower relative frequency of TNKCL; the prevalence of extranodal mucosa-associated lymphoid tissue lymphoma was much lower than in Korea, and the frequency of extranodal TNKCL, nasal type, was strikingly low compared to China. It is concluded that while the median age of Thai patients with NHL was approximately a decade younger than for Caucasians, the long-term survival rates for most histological subtypes were comparable. While the histological distribution generally complied with the characteristic Asian features, some differences from FEA were observed. Copyright © 2017 John Wiley & Sons, Ltd.
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85017382024&doi=10.1002%2fhon.2392&partnerID=40&md5=dbf345c17062800210dad4a14b237d9f
http://ir.swu.ac.th/jspui/handle/123456789/12812
ISSN: 2780232
Appears in Collections:Scopus 1983-2021

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