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Title: Bioactive 4-hydroxycinnamide and bioactivities of polyalthia cerasoides
Authors: Treeratanapiboon L.
Worachartcheewan A.
Suksrichavalit T.
Kiatfuengfoo R.
Prachayasittikul S.
Ruchirawat S.
Prachayasittikul V.
Keywords: 1,1 diphenyl 2 picrylhydrazyl
acetic acid ethyl ester
alpha tocopherol
antifungal agent
antiinfective agent
plant extract
plant medicinal product
Polyalthia cerasoides extract
superoxide dismutase
unclassified drug
antibacterial activity
antifungal activity
antioxidant activity
Bacillus cereus
Bacillus subtilis
Candida albicans
controlled study
Corynebacterium diphtheriae
drug isolation
drug structure
Gram negative bacterium
Gram positive bacterium
IC 50
Listeria monocytogenes
Micrococcus luteus
minimum inhibitory concentration
Plesiomonas shigelloides
Polyalthia cerasoides
Pseudomonas stutzeri
Saccharomyces cerevisiae
Salmonella choleraesuis
Salmonella typhimurium
Staphylococcus aureus
Staphylococcus epidermidis
Streptococcus pyogenes
Corynebacterium diphtheriae
Polyalthia cerasoides
Issue Date: 2011
Abstract: Constituents from Polyalthia cerasoides, stem bark methanol extract, were previously documented. This study reports the first isolation of bioactive N-(4-hydroxy-β-phenethyl)-4- hydroxycinnamide (1) from ethyl acetate extract of the plant species including stigmasterol and a mixture of triterpenes from hexane and dichloromethane extracts. Trace essential elements were found in the hexane extract in ppm level. The plant extracts were evaluated for their antimicrobial and antioxidative activities. The dichloromethane extract displayed the highest activity against Corynebacterium diphtheriae NCTC 10356 with MIC of 32 μg/mL, as well as, the highest SOD activity with an IC 50 of 4.51 μg/mL.
ISSN: 16112156
Appears in Collections:Scopus 1983-2021

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