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Title: Zinc deficiency in children with dengue viral infection
Authors: Rerksuppaphol L.
Rerksuppaphol S.
Keywords: alanine aminotransferase
aspartate aminotransferase
alanine aminotransferase blood level
aspartate aminotransferase level
blood sampling
body mass
child nutrition
clinical article
clinical feature
cross-sectional study
dengue hemorrhagic fever
disease duration
gastrointestinal hemorrhage
hypovolemic shock
length of stay
nausea and vomiting
pleura effusion
school child
Thai (people)
zinc blood level
zinc deficiency
Issue Date: 2019
Abstract: Zinc deficiency is highly prevalent in low-income countries, with dramatic consequences to child health, in particular by impairing the immune system resulting in infection. This cross-sectional study aimed to determine the prevalence of zinc deficiency in Thai children who were admitted to hospital with a diagnosis of the dengue viral infection. Standard cut-off values according to age, sex, time of blood collection, and fasting status were used to define zinc levels. 32 patients were included in the analysis: The mean age was 7.3 years, of whom 56.3% were males. 11 (34.4%) patients were diagnosed with dengue hemorrhagic fever and the remaining had dengue fever. The prevalence of zinc deficiency was 46.7%, with boys having a higher risk of zinc deficiency than girls (OR=7.3: 95%CI: 1.5-36.6). Fever duration and length of hospital stay were longer in children with zinc deficiency compared to those who had normal levels, albeit without a significant difference. The results of this study provide the rationale for larger studies that will better elucidate the relationship between zinc levels and the clinical outcomes of dengue disease. ©Copyright L. Rerksuppaphol and S. Rerksuppaphol, 2019.
ISSN: 20367503
Appears in Collections:Scopus 1983-2021

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